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Cutaneous and systematic metastasis of testicular choriocarcinoma: Case report and literature review
RATIONALE: Cutaneous metastasis of testicular choriocarcinoma is exceptionally uncommon. To our knowledge, only 14 cases have been reported in the past 10 years in the pubmed. We have an uncommon case of testicular choriocarcinoma who has metastasized to the adjacent skin and organ systems. PATIENT...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392768/ https://www.ncbi.nlm.nih.gov/pubmed/29851778 http://dx.doi.org/10.1097/MD.0000000000010736 |
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author | Weijin, Fu Jinjin, Zeng Jiwen, Cheng |
author_facet | Weijin, Fu Jinjin, Zeng Jiwen, Cheng |
author_sort | Weijin, Fu |
collection | PubMed |
description | RATIONALE: Cutaneous metastasis of testicular choriocarcinoma is exceptionally uncommon. To our knowledge, only 14 cases have been reported in the past 10 years in the pubmed. We have an uncommon case of testicular choriocarcinoma who has metastasized to the adjacent skin and organ systems. PATIENT CONCERNS: An 18-year-old male was diagnosed with initial presentation of cutaneous mass at the left back. Followly,biopsy was performed under local anesthesia.Histopathological examination was consistent with the diagnosis of metastatic choriocarcinoma. DIAGNOSES: The histopathological assessment of the biopsied tissue, in combination with elevated serum β-HCG levels and presentation of testicular mass, indicated primary testicular choriocarcinoma with cutaneous and systemic metastasis. INTERVENTIONS: Subsequently radical orchiectomy was performed. OUTCOMES: Despite the case completed one cycle of cisplatin-based regimen chemotherapy, he died of multiple organ dysfunction syndrome 2 months after surgery. LESSONS: In this report, cutaneous metastasis with testicular choriocarcinoma is extremely rare. It is important to recognize that this unusual variant of testicular choriocarcinoma has the potential to behave aggressively and to metastasize. |
format | Online Article Text |
id | pubmed-6392768 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-63927682019-03-15 Cutaneous and systematic metastasis of testicular choriocarcinoma: Case report and literature review Weijin, Fu Jinjin, Zeng Jiwen, Cheng Medicine (Baltimore) Research Article RATIONALE: Cutaneous metastasis of testicular choriocarcinoma is exceptionally uncommon. To our knowledge, only 14 cases have been reported in the past 10 years in the pubmed. We have an uncommon case of testicular choriocarcinoma who has metastasized to the adjacent skin and organ systems. PATIENT CONCERNS: An 18-year-old male was diagnosed with initial presentation of cutaneous mass at the left back. Followly,biopsy was performed under local anesthesia.Histopathological examination was consistent with the diagnosis of metastatic choriocarcinoma. DIAGNOSES: The histopathological assessment of the biopsied tissue, in combination with elevated serum β-HCG levels and presentation of testicular mass, indicated primary testicular choriocarcinoma with cutaneous and systemic metastasis. INTERVENTIONS: Subsequently radical orchiectomy was performed. OUTCOMES: Despite the case completed one cycle of cisplatin-based regimen chemotherapy, he died of multiple organ dysfunction syndrome 2 months after surgery. LESSONS: In this report, cutaneous metastasis with testicular choriocarcinoma is extremely rare. It is important to recognize that this unusual variant of testicular choriocarcinoma has the potential to behave aggressively and to metastasize. Wolters Kluwer Health 2018-06-01 /pmc/articles/PMC6392768/ /pubmed/29851778 http://dx.doi.org/10.1097/MD.0000000000010736 Text en Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 |
spellingShingle | Research Article Weijin, Fu Jinjin, Zeng Jiwen, Cheng Cutaneous and systematic metastasis of testicular choriocarcinoma: Case report and literature review |
title | Cutaneous and systematic metastasis of testicular choriocarcinoma: Case report and literature review |
title_full | Cutaneous and systematic metastasis of testicular choriocarcinoma: Case report and literature review |
title_fullStr | Cutaneous and systematic metastasis of testicular choriocarcinoma: Case report and literature review |
title_full_unstemmed | Cutaneous and systematic metastasis of testicular choriocarcinoma: Case report and literature review |
title_short | Cutaneous and systematic metastasis of testicular choriocarcinoma: Case report and literature review |
title_sort | cutaneous and systematic metastasis of testicular choriocarcinoma: case report and literature review |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392768/ https://www.ncbi.nlm.nih.gov/pubmed/29851778 http://dx.doi.org/10.1097/MD.0000000000010736 |
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