Cargando…

Helicobacter pylori eradication improves the quality of life regardless of the treatment outcome: A multicenter prospective cohort study

Helicobacter pylori (Hp) eradication is recommended for improving the quality of life (QOL) of patients with epigastric symptoms, especially reflux and dyspepsia. However, no reports have investigated the improvement of QOL after the eradication of Hp irrespective of epigastric symptoms. The aim of...

Descripción completa

Detalles Bibliográficos
Autores principales: Taguchi, Hiroki, Kanmura, Shuji, Maeda, Takuro, Iwaya, Hiromichi, Arima, Shiho, Sasaki, Fumisato, Nasu, Yuichirou, Tanoue, Shiroh, Hashimoto, Shinichi, Ido, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392891/
https://www.ncbi.nlm.nih.gov/pubmed/29384953
http://dx.doi.org/10.1097/MD.0000000000009507
_version_ 1783398576722804736
author Taguchi, Hiroki
Kanmura, Shuji
Maeda, Takuro
Iwaya, Hiromichi
Arima, Shiho
Sasaki, Fumisato
Nasu, Yuichirou
Tanoue, Shiroh
Hashimoto, Shinichi
Ido, Akio
author_facet Taguchi, Hiroki
Kanmura, Shuji
Maeda, Takuro
Iwaya, Hiromichi
Arima, Shiho
Sasaki, Fumisato
Nasu, Yuichirou
Tanoue, Shiroh
Hashimoto, Shinichi
Ido, Akio
author_sort Taguchi, Hiroki
collection PubMed
description Helicobacter pylori (Hp) eradication is recommended for improving the quality of life (QOL) of patients with epigastric symptoms, especially reflux and dyspepsia. However, no reports have investigated the improvement of QOL after the eradication of Hp irrespective of epigastric symptoms. The aim of this study was to investigate the improvement in the QOL after the eradication of Hp irrespective of epigastric symptoms, and evaluate the factors associated with an improved QOL after the eradication of Hp. This prospective cohort study was performed at 15 referral institutions from September 2013 to December 2014. The patients’ QOL and epigastric symptoms were evaluated before and after the eradication of Hp using the 8-item Short-Form Health Survey (SF-8) and the modified Frequency Scale for the Symptoms of Gastroesophageal Reflux Disease, respectively. One hundred sixty-five of 184 Hp-infected patients underwent Hp eradication treatment. The treatment was successful in 82.4% (136/165) of the cases. One hundred sixty of the 165 Hp-infected patients were eligible for inclusion in the QOL analysis. In the indices of QOL on the SF-8, the scores on both the mental component summary (MCS) and the physical component summary (PCS) were found to have significantly improved after the eradication of Hp. However, the epigastric symptoms before the eradication of Hp were not correlated with either the MCS or PCS. A low QOL value before the eradication of Hp was the factor what was most strongly associated with the improvement in the QOL. The eradication of Hp improved the QOL, regardless of the outcome of the treatment, especially in patients who had an impaired QOL before the eradication.
format Online
Article
Text
id pubmed-6392891
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Wolters Kluwer Health
record_format MEDLINE/PubMed
spelling pubmed-63928912019-03-15 Helicobacter pylori eradication improves the quality of life regardless of the treatment outcome: A multicenter prospective cohort study Taguchi, Hiroki Kanmura, Shuji Maeda, Takuro Iwaya, Hiromichi Arima, Shiho Sasaki, Fumisato Nasu, Yuichirou Tanoue, Shiroh Hashimoto, Shinichi Ido, Akio Medicine (Baltimore) Research Article Helicobacter pylori (Hp) eradication is recommended for improving the quality of life (QOL) of patients with epigastric symptoms, especially reflux and dyspepsia. However, no reports have investigated the improvement of QOL after the eradication of Hp irrespective of epigastric symptoms. The aim of this study was to investigate the improvement in the QOL after the eradication of Hp irrespective of epigastric symptoms, and evaluate the factors associated with an improved QOL after the eradication of Hp. This prospective cohort study was performed at 15 referral institutions from September 2013 to December 2014. The patients’ QOL and epigastric symptoms were evaluated before and after the eradication of Hp using the 8-item Short-Form Health Survey (SF-8) and the modified Frequency Scale for the Symptoms of Gastroesophageal Reflux Disease, respectively. One hundred sixty-five of 184 Hp-infected patients underwent Hp eradication treatment. The treatment was successful in 82.4% (136/165) of the cases. One hundred sixty of the 165 Hp-infected patients were eligible for inclusion in the QOL analysis. In the indices of QOL on the SF-8, the scores on both the mental component summary (MCS) and the physical component summary (PCS) were found to have significantly improved after the eradication of Hp. However, the epigastric symptoms before the eradication of Hp were not correlated with either the MCS or PCS. A low QOL value before the eradication of Hp was the factor what was most strongly associated with the improvement in the QOL. The eradication of Hp improved the QOL, regardless of the outcome of the treatment, especially in patients who had an impaired QOL before the eradication. Wolters Kluwer Health 2017-12-29 /pmc/articles/PMC6392891/ /pubmed/29384953 http://dx.doi.org/10.1097/MD.0000000000009507 Text en Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle Research Article
Taguchi, Hiroki
Kanmura, Shuji
Maeda, Takuro
Iwaya, Hiromichi
Arima, Shiho
Sasaki, Fumisato
Nasu, Yuichirou
Tanoue, Shiroh
Hashimoto, Shinichi
Ido, Akio
Helicobacter pylori eradication improves the quality of life regardless of the treatment outcome: A multicenter prospective cohort study
title Helicobacter pylori eradication improves the quality of life regardless of the treatment outcome: A multicenter prospective cohort study
title_full Helicobacter pylori eradication improves the quality of life regardless of the treatment outcome: A multicenter prospective cohort study
title_fullStr Helicobacter pylori eradication improves the quality of life regardless of the treatment outcome: A multicenter prospective cohort study
title_full_unstemmed Helicobacter pylori eradication improves the quality of life regardless of the treatment outcome: A multicenter prospective cohort study
title_short Helicobacter pylori eradication improves the quality of life regardless of the treatment outcome: A multicenter prospective cohort study
title_sort helicobacter pylori eradication improves the quality of life regardless of the treatment outcome: a multicenter prospective cohort study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392891/
https://www.ncbi.nlm.nih.gov/pubmed/29384953
http://dx.doi.org/10.1097/MD.0000000000009507
work_keys_str_mv AT taguchihiroki helicobacterpylorieradicationimprovesthequalityofliferegardlessofthetreatmentoutcomeamulticenterprospectivecohortstudy
AT kanmurashuji helicobacterpylorieradicationimprovesthequalityofliferegardlessofthetreatmentoutcomeamulticenterprospectivecohortstudy
AT maedatakuro helicobacterpylorieradicationimprovesthequalityofliferegardlessofthetreatmentoutcomeamulticenterprospectivecohortstudy
AT iwayahiromichi helicobacterpylorieradicationimprovesthequalityofliferegardlessofthetreatmentoutcomeamulticenterprospectivecohortstudy
AT arimashiho helicobacterpylorieradicationimprovesthequalityofliferegardlessofthetreatmentoutcomeamulticenterprospectivecohortstudy
AT sasakifumisato helicobacterpylorieradicationimprovesthequalityofliferegardlessofthetreatmentoutcomeamulticenterprospectivecohortstudy
AT nasuyuichirou helicobacterpylorieradicationimprovesthequalityofliferegardlessofthetreatmentoutcomeamulticenterprospectivecohortstudy
AT tanoueshiroh helicobacterpylorieradicationimprovesthequalityofliferegardlessofthetreatmentoutcomeamulticenterprospectivecohortstudy
AT hashimotoshinichi helicobacterpylorieradicationimprovesthequalityofliferegardlessofthetreatmentoutcomeamulticenterprospectivecohortstudy
AT idoakio helicobacterpylorieradicationimprovesthequalityofliferegardlessofthetreatmentoutcomeamulticenterprospectivecohortstudy