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Perianal ulcerative skin tuberculosis: A case report

RATIONALE: Ulcerative skin tuberculosis (TB) is a rare form of extrapulmonary TB. CASE REPORT: We present a case of a 65-year-old patient with perianal ulcer, which had been present for 1 year. Anamnesis revealed he had been persistently coughing for the same period of time. Histological examination...

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Autores principales: Wu, Shaofang, Wang, Wu, Chen, Huan, Xiong, Wen, Song, Xin, Yu, Xinmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392906/
https://www.ncbi.nlm.nih.gov/pubmed/29851791
http://dx.doi.org/10.1097/MD.0000000000010836
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author Wu, Shaofang
Wang, Wu
Chen, Huan
Xiong, Wen
Song, Xin
Yu, Xinmin
author_facet Wu, Shaofang
Wang, Wu
Chen, Huan
Xiong, Wen
Song, Xin
Yu, Xinmin
author_sort Wu, Shaofang
collection PubMed
description RATIONALE: Ulcerative skin tuberculosis (TB) is a rare form of extrapulmonary TB. CASE REPORT: We present a case of a 65-year-old patient with perianal ulcer, which had been present for 1 year. Anamnesis revealed he had been persistently coughing for the same period of time. Histological examination of perianal skin showed necrotizing granulomatous lesions, acid-fast staining in sputum samples was ++++, TB antibody in the blood was positive, TB DNA test was positive, and chest scan that showed secondary pulmonary TB accompanied by possible pulmonary cavity formation in the 2 upper lungs. INTERVENTIONS: Anti-TB therapy with isoniazid, rifampicin, ethambutol, and pyrazinamide for 6 months. The skin ulcer completely healed after 6 months. CONCLUSION: TB should be suspected for nonhealing ulcers. Pertinent studies should be done early during the lesion; finally, TB treatment should be initiated immediately after diagnosis is made.
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spelling pubmed-63929062019-03-15 Perianal ulcerative skin tuberculosis: A case report Wu, Shaofang Wang, Wu Chen, Huan Xiong, Wen Song, Xin Yu, Xinmin Medicine (Baltimore) Research Article RATIONALE: Ulcerative skin tuberculosis (TB) is a rare form of extrapulmonary TB. CASE REPORT: We present a case of a 65-year-old patient with perianal ulcer, which had been present for 1 year. Anamnesis revealed he had been persistently coughing for the same period of time. Histological examination of perianal skin showed necrotizing granulomatous lesions, acid-fast staining in sputum samples was ++++, TB antibody in the blood was positive, TB DNA test was positive, and chest scan that showed secondary pulmonary TB accompanied by possible pulmonary cavity formation in the 2 upper lungs. INTERVENTIONS: Anti-TB therapy with isoniazid, rifampicin, ethambutol, and pyrazinamide for 6 months. The skin ulcer completely healed after 6 months. CONCLUSION: TB should be suspected for nonhealing ulcers. Pertinent studies should be done early during the lesion; finally, TB treatment should be initiated immediately after diagnosis is made. Wolters Kluwer Health 2018-06-01 /pmc/articles/PMC6392906/ /pubmed/29851791 http://dx.doi.org/10.1097/MD.0000000000010836 Text en Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle Research Article
Wu, Shaofang
Wang, Wu
Chen, Huan
Xiong, Wen
Song, Xin
Yu, Xinmin
Perianal ulcerative skin tuberculosis: A case report
title Perianal ulcerative skin tuberculosis: A case report
title_full Perianal ulcerative skin tuberculosis: A case report
title_fullStr Perianal ulcerative skin tuberculosis: A case report
title_full_unstemmed Perianal ulcerative skin tuberculosis: A case report
title_short Perianal ulcerative skin tuberculosis: A case report
title_sort perianal ulcerative skin tuberculosis: a case report
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392906/
https://www.ncbi.nlm.nih.gov/pubmed/29851791
http://dx.doi.org/10.1097/MD.0000000000010836
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