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Giant sellar metastasis from renal cell carcinoma: A case report and literature review

RATIONALE: Sellar metastasis is a rare and complex disease whose clinical features are strongly associated with the primary malignancy. Here, we present a rare case of giant sellar metastasis spread from renal cell carcinoma (RCC). PATIENT CONCERNS: A 30-year-old Chinese woman was admitted to our Ho...

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Autores principales: Shen, Zhiwei, Yang, Chengxian, Bao, Xinjie, Wang, Renzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392949/
https://www.ncbi.nlm.nih.gov/pubmed/30461658
http://dx.doi.org/10.1097/MD.0000000000013376
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author Shen, Zhiwei
Yang, Chengxian
Bao, Xinjie
Wang, Renzhi
author_facet Shen, Zhiwei
Yang, Chengxian
Bao, Xinjie
Wang, Renzhi
author_sort Shen, Zhiwei
collection PubMed
description RATIONALE: Sellar metastasis is a rare and complex disease whose clinical features are strongly associated with the primary malignancy. Here, we present a rare case of giant sellar metastasis spread from renal cell carcinoma (RCC). PATIENT CONCERNS: A 30-year-old Chinese woman was admitted to our Hospital, reporting headache, nasal congestion, nausea, vomiting, and a sharp decline in her right eye vision. DIAGNOSES: Brain magnetic resonance imaging (MRI) revealed an invasive sellar mass with cavernous sinus and nasal cavity extension. Additionally, the patient had a medical history of right radical nephrectomy for clear-cell RCC. INTERVENTIONS: The patient underwent a successful subtotal resection of the tumor. Final pathological diagnosis confirmed sellar metastasis from RCC. After surgery, the patient was referred to our medical oncology department and received further systemic therapy. OUTCOMES: No light perception remained in her right eye even after prompt surgical decompression. Follow-up MRI showed subtotal resection of the giant sellar metastasis. LESSON: Sellar metastasis, although rare, should be particularly considered for elderly patients with deteriorating visual function and medical histories of cancer.
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spelling pubmed-63929492019-03-15 Giant sellar metastasis from renal cell carcinoma: A case report and literature review Shen, Zhiwei Yang, Chengxian Bao, Xinjie Wang, Renzhi Medicine (Baltimore) Research Article RATIONALE: Sellar metastasis is a rare and complex disease whose clinical features are strongly associated with the primary malignancy. Here, we present a rare case of giant sellar metastasis spread from renal cell carcinoma (RCC). PATIENT CONCERNS: A 30-year-old Chinese woman was admitted to our Hospital, reporting headache, nasal congestion, nausea, vomiting, and a sharp decline in her right eye vision. DIAGNOSES: Brain magnetic resonance imaging (MRI) revealed an invasive sellar mass with cavernous sinus and nasal cavity extension. Additionally, the patient had a medical history of right radical nephrectomy for clear-cell RCC. INTERVENTIONS: The patient underwent a successful subtotal resection of the tumor. Final pathological diagnosis confirmed sellar metastasis from RCC. After surgery, the patient was referred to our medical oncology department and received further systemic therapy. OUTCOMES: No light perception remained in her right eye even after prompt surgical decompression. Follow-up MRI showed subtotal resection of the giant sellar metastasis. LESSON: Sellar metastasis, although rare, should be particularly considered for elderly patients with deteriorating visual function and medical histories of cancer. Wolters Kluwer Health 2018-11-21 /pmc/articles/PMC6392949/ /pubmed/30461658 http://dx.doi.org/10.1097/MD.0000000000013376 Text en Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0
spellingShingle Research Article
Shen, Zhiwei
Yang, Chengxian
Bao, Xinjie
Wang, Renzhi
Giant sellar metastasis from renal cell carcinoma: A case report and literature review
title Giant sellar metastasis from renal cell carcinoma: A case report and literature review
title_full Giant sellar metastasis from renal cell carcinoma: A case report and literature review
title_fullStr Giant sellar metastasis from renal cell carcinoma: A case report and literature review
title_full_unstemmed Giant sellar metastasis from renal cell carcinoma: A case report and literature review
title_short Giant sellar metastasis from renal cell carcinoma: A case report and literature review
title_sort giant sellar metastasis from renal cell carcinoma: a case report and literature review
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392949/
https://www.ncbi.nlm.nih.gov/pubmed/30461658
http://dx.doi.org/10.1097/MD.0000000000013376
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