Cargando…

Dynamics of intracellular stress-induced tRNA trafficking

Stress is known to induce retrograde tRNA translocation from the cytoplasm to the nucleus but translocation kinetics and tRNA-spatial distribution have not been characterized previously. We microinject fluorescently-labeled tRNA into living cells and use confocal microscopy to image tRNA spatial dis...

Descripción completa

Detalles Bibliográficos
Autores principales: Dhakal, Rabin, Tong, Chunyi, Anderson, Sean, Kashina, Anna S, Cooperman, Barry, Bau, Haim H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393242/
https://www.ncbi.nlm.nih.gov/pubmed/30496477
http://dx.doi.org/10.1093/nar/gky1208