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Preclinical Safety Evaluation of Ophthalmic Viscosurgical Devices in Rabbits and a Novel Mini-Pig Model

INTRODUCTION: To establish the preclinical safety and equivalency of ophthalmic viscosurgical devices (OVDs) comprised of bacterially sourced sodium hyaluronate (HA) to animal sourced HA using pyrogenicity and aqueous exchange models in rabbits and a novel mini-pig model to evaluate corneal endothel...

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Detalles Bibliográficos
Autores principales: Leang, Ronika S., Kloft, Lisa J., Gray, Brad, Gwon, Arlene E., Huang, Ling C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393256/
https://www.ncbi.nlm.nih.gov/pubmed/30778776
http://dx.doi.org/10.1007/s40123-019-0167-9

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