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Archaeal NSUN6 catalyzes m(5)C72 modification on a wide-range of specific tRNAs

Human NOL1/NOP2/Sun RNA methyltransferase family member 6 (hNSun6) generates 5-methylcytosine (m(5)C) at C72 of four specific tRNAs, and its homologs are present only in higher eukaryotes and hyperthermophilic archaea. Archaeal NSun6 homologs possess conserved catalytic residues, but have distinct d...

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Detalles Bibliográficos
Autores principales: Li, Jing, Li, Hao, Long, Tao, Dong, Han, Wang, En-Duo, Liu, Ru-Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393295/
https://www.ncbi.nlm.nih.gov/pubmed/30541086
http://dx.doi.org/10.1093/nar/gky1236