Protease-activated receptor 2 protects against VEGF inhibitor-induced glomerular endothelial and podocyte injury

Vascular endothelial growth factor (VEGF) inhibitors cause glomerular injury. We have recently shown that activation of protease-activated receptor 2 (PAR2) by factor Xa exacerbated diabetic kidney disease. However, the role of PAR2 in glomerular injury induced by VEGF blockade is not known. Herein,...

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Detalles Bibliográficos
Autores principales: Oe, Yuji, Fushima, Tomofumi, Sato, Emiko, Sekimoto, Akiyo, Kisu, Kiyomi, Sato, Hiroshi, Sugawara, Junichi, Ito, Sadayoshi, Takahashi, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393426/
https://www.ncbi.nlm.nih.gov/pubmed/30814628
http://dx.doi.org/10.1038/s41598-019-39914-8

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