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Omegasome-proximal PtdIns(4,5)P(2) couples F-actin mediated mitoaggregate disassembly with autophagosome formation during mitophagy
Cells govern their homeostasis through autophagy by sequestering substrates, ranging from proteins to aggregates and organelles, into autophagosomes for lysosomal degradation. In these processes cells need to coordinate between substrate remodeling and autophagosome formation for efficient engulfmen...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393429/ https://www.ncbi.nlm.nih.gov/pubmed/30814505 http://dx.doi.org/10.1038/s41467-019-08924-5 |