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Long fragments achieve lower base quality in Illumina paired-end sequencing
Illumina’s technology provides high quality reads of DNA fragments with error rates below 1/1000 per base. Sequencing runs typically generate millions of reads in which the vast majority of the reads has an average error rate below 1/1000. However, some paired-end sequencing data show the presence o...
Autores principales: | Tan, Ge, Opitz, Lennart, Schlapbach, Ralph, Rehrauer, Hubert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393434/ https://www.ncbi.nlm.nih.gov/pubmed/30814542 http://dx.doi.org/10.1038/s41598-019-39076-7 |
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