A Novel Optical Scanning Technique with an Inclined Focusing Plane

We propose a novel technique for fully automated optical scanning of thin samples. We analyze its performance and estimate the achievable scanning speed to compare it with conventional techniques. It paves the way to the next generation of highspeed scalable scanning systems, at least one order of m...

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Autores principales: Alexandrov, Andrey, De Lellis, Giovanni, Tioukov, Valeri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393444/
https://www.ncbi.nlm.nih.gov/pubmed/30814578
http://dx.doi.org/10.1038/s41598-019-39415-8
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author Alexandrov, Andrey
De Lellis, Giovanni
Tioukov, Valeri
author_facet Alexandrov, Andrey
De Lellis, Giovanni
Tioukov, Valeri
author_sort Alexandrov, Andrey
collection PubMed
description We propose a novel technique for fully automated optical scanning of thin samples. We analyze its performance and estimate the achievable scanning speed to compare it with conventional techniques. It paves the way to the next generation of highspeed scalable scanning systems, at least one order of magnitude faster than existing ones. We show that the efficiency and the accuracy of this new technique are comparable to those of the conventional ones, while the scanning speed scales proportionally with the number of cameras installed, hence the large expected improvement.
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spelling pubmed-63934442019-03-01 A Novel Optical Scanning Technique with an Inclined Focusing Plane Alexandrov, Andrey De Lellis, Giovanni Tioukov, Valeri Sci Rep Article We propose a novel technique for fully automated optical scanning of thin samples. We analyze its performance and estimate the achievable scanning speed to compare it with conventional techniques. It paves the way to the next generation of highspeed scalable scanning systems, at least one order of magnitude faster than existing ones. We show that the efficiency and the accuracy of this new technique are comparable to those of the conventional ones, while the scanning speed scales proportionally with the number of cameras installed, hence the large expected improvement. Nature Publishing Group UK 2019-02-27 /pmc/articles/PMC6393444/ /pubmed/30814578 http://dx.doi.org/10.1038/s41598-019-39415-8 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Alexandrov, Andrey
De Lellis, Giovanni
Tioukov, Valeri
A Novel Optical Scanning Technique with an Inclined Focusing Plane
title A Novel Optical Scanning Technique with an Inclined Focusing Plane
title_full A Novel Optical Scanning Technique with an Inclined Focusing Plane
title_fullStr A Novel Optical Scanning Technique with an Inclined Focusing Plane
title_full_unstemmed A Novel Optical Scanning Technique with an Inclined Focusing Plane
title_short A Novel Optical Scanning Technique with an Inclined Focusing Plane
title_sort novel optical scanning technique with an inclined focusing plane
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393444/
https://www.ncbi.nlm.nih.gov/pubmed/30814578
http://dx.doi.org/10.1038/s41598-019-39415-8
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