Circulating myocardial microRNAs from infarcted hearts are carried in exosomes and mobilise bone marrow progenitor cells

Myocardial microRNAs (myo-miRs) are released into the circulation after acute myocardial infarction (AMI). How they impact remote organs is however largely unknown. Here we show that circulating myo-miRs are carried in exosomes and mediate functional crosstalk between the ischemic heart and the bone...

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Detalles Bibliográficos
Autores principales: Cheng, Min, Yang, Junjie, Zhao, Xiaoqi, Zhang, Eric, Zeng, Qiutang, Yu, Yang, Yang, Liu, Wu, Bangwei, Yi, Guiwen, Mao, Xiaobo, Huang, Kai, Dong, Nianguo, Xie, Min, Limdi, Nita A., Prabhu, Sumanth D., Zhang, Jianyi, Qin, Gangjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393447/
https://www.ncbi.nlm.nih.gov/pubmed/30814518
http://dx.doi.org/10.1038/s41467-019-08895-7

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