A novel mutation tolerant padlock probe design for multiplexed detection of hypervariable RNA viruses

The establishment of a robust detection platform for RNA viruses still remains a challenge in molecular diagnostics due to their high mutation rates. Newcastle disease virus (NDV) is one such RNA avian virus with a hypervariable genome and multiple genotypes. Classical approaches like virus isolatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Ciftci, Sibel, Neumann, Felix, Hernández-Neuta, Iván, Hakhverdyan, Mikhayil, Bálint, Ádám, Herthnek, David, Madaboosi, Narayanan, Nilsson, Mats
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393471/
https://www.ncbi.nlm.nih.gov/pubmed/30814634
http://dx.doi.org/10.1038/s41598-019-39854-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393471/
https://www.ncbi.nlm.nih.gov/pubmed/30814634
http://dx.doi.org/10.1038/s41598-019-39854-3

Ejemplares similares