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A novel mutation tolerant padlock probe design for multiplexed detection of hypervariable RNA viruses
The establishment of a robust detection platform for RNA viruses still remains a challenge in molecular diagnostics due to their high mutation rates. Newcastle disease virus (NDV) is one such RNA avian virus with a hypervariable genome and multiple genotypes. Classical approaches like virus isolatio...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393471/ https://www.ncbi.nlm.nih.gov/pubmed/30814634 http://dx.doi.org/10.1038/s41598-019-39854-3 |