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Gold-Plated Electrode with High Scratch Strength for Electrophysiological Recordings

Multi electrode arrays (MEA) have been exploited in different electrophysiological applications. In neurological applications, MEAs are the vital interfaces between neurons and the electronic circuits with dual role; transmitting electric signal to the neurons and converting neural activity to the e...

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Autores principales: Vafaiee, Mohaddeseh, Vossoughi, Manouchehr, Mohammadpour, Raheleh, Sasanpour, Pezhman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393511/
https://www.ncbi.nlm.nih.gov/pubmed/30814648
http://dx.doi.org/10.1038/s41598-019-39138-w
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author Vafaiee, Mohaddeseh
Vossoughi, Manouchehr
Mohammadpour, Raheleh
Sasanpour, Pezhman
author_facet Vafaiee, Mohaddeseh
Vossoughi, Manouchehr
Mohammadpour, Raheleh
Sasanpour, Pezhman
author_sort Vafaiee, Mohaddeseh
collection PubMed
description Multi electrode arrays (MEA) have been exploited in different electrophysiological applications. In neurological applications, MEAs are the vital interfaces between neurons and the electronic circuits with dual role; transmitting electric signal to the neurons and converting neural activity to the electric signal. Since the performance of the electrodes has a direct effect on the quality of the recorded neuronal signal, as well as the stimulation, the true choice of electrode material for MEA is crucial. Gold is one of the best candidates for fabrication of MEAs due to its high electrical conductivity, biocompatibility and good chemical stability. However, noble metals such as gold do not adhere well to the glass substrate. Consequently while exposing to the water, gold films are damaged, which impose limitations in the exploiting of gold thin films as the electrode. In this paper, a simple and cost effective method for the fabrication of gold electrode arrays is proposed. Using various mechanical (adhesion test and scratch strength), morphological (AFM and SEM) and electrochemical methods, the fabricated electrodes are characterized. The results show that the fabricated electrode arrays have significantly high scratch strength and stability within the aqueous medium. In addition, the electrical properties of the electrodes have been improved. The proposed electrodes have the potential to be exploited in other applications including electronics, electrochemistry, and biosensors.
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spelling pubmed-63935112019-03-01 Gold-Plated Electrode with High Scratch Strength for Electrophysiological Recordings Vafaiee, Mohaddeseh Vossoughi, Manouchehr Mohammadpour, Raheleh Sasanpour, Pezhman Sci Rep Article Multi electrode arrays (MEA) have been exploited in different electrophysiological applications. In neurological applications, MEAs are the vital interfaces between neurons and the electronic circuits with dual role; transmitting electric signal to the neurons and converting neural activity to the electric signal. Since the performance of the electrodes has a direct effect on the quality of the recorded neuronal signal, as well as the stimulation, the true choice of electrode material for MEA is crucial. Gold is one of the best candidates for fabrication of MEAs due to its high electrical conductivity, biocompatibility and good chemical stability. However, noble metals such as gold do not adhere well to the glass substrate. Consequently while exposing to the water, gold films are damaged, which impose limitations in the exploiting of gold thin films as the electrode. In this paper, a simple and cost effective method for the fabrication of gold electrode arrays is proposed. Using various mechanical (adhesion test and scratch strength), morphological (AFM and SEM) and electrochemical methods, the fabricated electrodes are characterized. The results show that the fabricated electrode arrays have significantly high scratch strength and stability within the aqueous medium. In addition, the electrical properties of the electrodes have been improved. The proposed electrodes have the potential to be exploited in other applications including electronics, electrochemistry, and biosensors. Nature Publishing Group UK 2019-02-27 /pmc/articles/PMC6393511/ /pubmed/30814648 http://dx.doi.org/10.1038/s41598-019-39138-w Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Vafaiee, Mohaddeseh
Vossoughi, Manouchehr
Mohammadpour, Raheleh
Sasanpour, Pezhman
Gold-Plated Electrode with High Scratch Strength for Electrophysiological Recordings
title Gold-Plated Electrode with High Scratch Strength for Electrophysiological Recordings
title_full Gold-Plated Electrode with High Scratch Strength for Electrophysiological Recordings
title_fullStr Gold-Plated Electrode with High Scratch Strength for Electrophysiological Recordings
title_full_unstemmed Gold-Plated Electrode with High Scratch Strength for Electrophysiological Recordings
title_short Gold-Plated Electrode with High Scratch Strength for Electrophysiological Recordings
title_sort gold-plated electrode with high scratch strength for electrophysiological recordings
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393511/
https://www.ncbi.nlm.nih.gov/pubmed/30814648
http://dx.doi.org/10.1038/s41598-019-39138-w
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