Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism

Dynamic metabolic changes occur in the liver during the transition between fasting and feeding. Here we show that transient ER stress responses in the liver following feeding terminated by Sdf2l1 are essential for normal glucose and lipid homeostasis. Sdf2l1 regulates ERAD through interaction with a...

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Detalles Bibliográficos
Autores principales: Sasako, Takayoshi, Ohsugi, Mitsuru, Kubota, Naoto, Itoh, Shinsuke, Okazaki, Yukiko, Terai, Ai, Kubota, Tetsuya, Yamashita, Satoshi, Nakatsukasa, Kunio, Kamura, Takumi, Iwayama, Kaito, Tokuyama, Kumpei, Kiyonari, Hiroshi, Furuta, Yasuhide, Shibahara, Junji, Fukayama, Masashi, Enooku, Kenichiro, Okushin, Kazuya, Tsutsumi, Takeya, Tateishi, Ryosuke, Tobe, Kazuyuki, Asahara, Hiroshi, Koike, Kazuhiko, Kadowaki, Takashi, Ueki, Kohjiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393527/
https://www.ncbi.nlm.nih.gov/pubmed/30814508
http://dx.doi.org/10.1038/s41467-019-08591-6

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