PPARδ attenuates hepatic steatosis through autophagy-mediated fatty acid oxidation

Peroxisome proliferator-activated receptor δ (PPARδ) belongs to the nuclear receptor family and is involved in metabolic diseases. Although PPARδ is known to attenuate hepatic lipid deposition, its mechanism remains unclear. Here, we show that PPARδ is a potent stimulator of hepatic autophagic flux....

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Detalles Bibliográficos
Autores principales: Tong, Lei, Wang, Long, Yao, Shuangshuang, Jin, Lina, Yang, Jian, Zhang, Yifei, Ning, Guang, Zhang, Zhiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393554/
https://www.ncbi.nlm.nih.gov/pubmed/30814493
http://dx.doi.org/10.1038/s41419-019-1458-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393554/
https://www.ncbi.nlm.nih.gov/pubmed/30814493
http://dx.doi.org/10.1038/s41419-019-1458-8

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