MTA2-mediated inhibition of PTEN leads to pancreatic ductal adenocarcinoma carcinogenicity

Metastasis-associated protein 2 (MTA2) is a core subunit of the nucleosome remodeling and deacetylating (NuRD) complex and functions by mediating chromatin remodeling and gene silencing. However, its biological actions and clinical significance in pancreatic ductal adenocarcinoma (PDAC) remain elusi...

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Detalles Bibliográficos
Autores principales: Si, Wenzhe, Liu, Xujun, Wei, Rui, Zhang, Yuan, Zhao, Yang, Cui, Liyan, Hong, Tianpei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393561/
https://www.ncbi.nlm.nih.gov/pubmed/30814496
http://dx.doi.org/10.1038/s41419-019-1424-5

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