Cargando…

The Legionella effector LtpM is a new type of phosphoinositide-activated glucosyltransferase

Legionella pneumophila causes Legionnaires' disease, a severe form of pneumonia. L. pneumophila translocates more than 300 effectors into host cells via its Dot/Icm (Defective in organelle trafficking/Intracellular multiplication) type IV secretion system to enable its replication in target cel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Levanova, Nadezhda, Mattheis, Corinna, Carson, Danielle, To, Ka-Ning, Jank, Thomas, Frankel, Gad, Aktories, Klaus, Schroeder, Gunnar Neels
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2019
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393602/ https://www.ncbi.nlm.nih.gov/pubmed/30573678 http://dx.doi.org/10.1074/jbc.RA118.005952

Ejemplares similares

Aminoacyl-tRNA-Charged Eukaryotic Elongation Factor 1A Is the Bona Fide Substrate for Legionella pneumophila Effector Glucosyltransferases
por: Tzivelekidis, Tina, et al.
Publicado: (2011)

Effector Glycosyltransferases in Legionella
por: Belyi, Yury, et al.
Publicado: (2011)

Glycosylating Effectors of Legionella pneumophila: Finding the Sweet Spots for Host Cell Subversion
por: Belyi, Yury, et al.
Publicado: (2022)

Anchors for Effectors: Subversion of Phosphoinositide Lipids by Legionella
por: Hilbi, Hubert, et al.
Publicado: (2011)

Phosphoinositides and the Fate of Legionella in Phagocytes
por: Swart, A. Leoni, et al.
Publicado: (2020)

The Rab-binding Profiles of Bacterial Virulence Factors during Infection
por: So, Ernest C., et al.
Publicado: (2016)

Use of Galleria mellonella as a Model Organism to Study Legionella pneumophila Infection
por: Harding, Clare R., et al.
Publicado: (2013)

A New Method To Determine In Vivo Interactomes Reveals Binding of the Legionella pneumophila Effector PieE to Multiple Rab GTPases
por: Mousnier, Aurélie, et al.
Publicado: (2014)

The Toolbox for Uncovering the Functions of Legionella Dot/Icm Type IVb Secretion System Effectors: Current State and Future Directions
por: Schroeder, Gunnar N.
Publicado: (2018)

An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway
por: Shin, Hye-Won, et al.
Publicado: (2005)

Affecting the Effectors: Regulation of Legionella pneumophila Effector Function by Metaeffectors
por: Joseph, Ashley M., et al.
Publicado: (2021)

Live-Cell Imaging of Phosphoinositide Dynamics and Membrane Architecture during Legionella Infection
por: Weber, Stephen, et al.
Publicado: (2014)

Ubiquitin-regulating effector proteins from Legionella
por: Jeong, Minwoo, et al.
Publicado: (2022)

Monitoring Phosphoinositide Fluxes and Effectors During Leukocyte Chemotaxis and Phagocytosis
por: Montaño-Rendón, Fernando, et al.
Publicado: (2021)

Divergence of Legionella Effectors Reversing Conventional and Unconventional Ubiquitination
por: Kitao, Tomoe, et al.
Publicado: (2020)

Regulation of PI3K effector signalling in cancer by the phosphoinositide phosphatases
por: Rodgers, Samuel J., et al.
Publicado: (2017)

The mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector
por: Akturk, Anil, et al.
Publicado: (2018)

Evolution of the Arsenal of Legionella pneumophila Effectors To Modulate Protist Hosts
por: Best, Ashley, et al.
Publicado: (2018)

A Legionella effector ADP-ribosyltransferase inactivates glutamate dehydrogenase
por: Black, Miles H., et al.
Publicado: (2021)

Structural and Functional Characterization of Legionella pneumophila Effector MavL
por: Voth, Kevin, et al.
Publicado: (2021)

Legionella para-effectors target chromatin and promote bacterial replication
por: Schator, Daniel, et al.
Publicado: (2023)

Structural basis for the toxicity of Legionella pneumophila effector SidH
por: Sharma, Rahul, et al.
Publicado: (2023)

Advances and Challenges in Studying Type III Secretion Effectors of Attaching and Effacing Pathogens
por: Slater, Sabrina L., et al.
Publicado: (2020)

Bioconversion of Corticosterone into Corticosterone-Glucoside by Glucosyltransferase
por: Yamaguchi, Tokutaro, et al.
Publicado: (2018)

Evolutionary diversification of cytokinin-specific glucosyltransferases in angiosperms and enigma of missing cis-zeatin O-glucosyltransferase gene in Brassicaceae
por: Záveská Drábková, Lenka, et al.
Publicado: (2021)

A Search for Novel Legionella pneumophila Effector Proteins Reveals a Strain Specific Nucleotropic Effector
por: Monteiro, Inês P., et al.
Publicado: (2022)

A new Rab7 effector controls phosphoinositide conversion in endosome maturation
por: Casanova, James E., et al.
Publicado: (2017)

Modification of phosphoinositides by the Shigella effector IpgD during host cell infection
por: Tran Van Nhieu, Guy, et al.
Publicado: (2022)

Combined LTP Sublingual and Oral Immunotherapy in LTP Syndrome: Efficacy and Safety
por: Martin Iglesias, Maria Aranzazu, et al.
Publicado: (2023)

Legionella Metaeffector Exploits Host Proteasome to Temporally Regulate Cognate Effector
por: Kubori, Tomoko, et al.
Publicado: (2010)

Identification of Two Legionella pneumophila Effectors that Manipulate Host Phospholipids Biosynthesis
por: Viner, Ram, et al.
Publicado: (2012)

Subversion of Cell-Autonomous Immunity and Cell Migration by Legionella pneumophila Effectors
por: Simon, Sylvia, et al.
Publicado: (2015)

A Legionella Effector Disrupts Host Cytoskeletal Structure by Cleaving Actin
por: Liu, Yao, et al.
Publicado: (2017)

Insights into the ubiquitin transfer cascade catalyzed by the Legionella effector SidC
por: Wasilko, David Jon, et al.
Publicado: (2018)

Molecular mechanism for the subversion of the retromer coat by the Legionella effector RidL
por: Romano-Moreno, Miguel, et al.
Publicado: (2017)

Host FIH-Mediated Asparaginyl Hydroxylation of Translocated Legionella pneumophila Effectors
por: Price, Christopher, et al.
Publicado: (2017)

An Indispensable Role for the MavE Effector of Legionella pneumophila in Lysosomal Evasion
por: Vaughn, Bethany, et al.
Publicado: (2021)

Acceptors and Effectors Alter Substrate Inhibition Kinetics of a Plant Glucosyltransferase NbUGT72AY1 and Its Mutants
por: Liao, Jieren, et al.
Publicado: (2023)

The UDP-glucosyltransferase multigene family in Bombyx mori
por: Huang, Fei-Fei, et al.
Publicado: (2008)

An Update on the Evolution of Glucosyltransferase (Gtf) Genes in Streptococcus
por: Xu, Rong-Rong, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ktgpr3hkalg4c98vi6svek96cm