Coupled monoubiquitylation of the co-E3 ligase DCNL1 by Ariadne-RBR E3 ubiquitin ligases promotes cullin-RING ligase complex remodeling

Cullin-RING E3 ubiquitin ligases (CRLs) are large and diverse multisubunit protein complexes that contribute to about one-fifth of ubiquitin-dependent protein turnover in cells. CRLs are activated by the attachment of the ubiquitin-like protein neural precursor cell expressed, developmentally down-r...

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Detalles Bibliográficos
Autores principales: Kelsall, Ian R., Kristariyanto, Yosua A., Knebel, Axel, Wood, Nicola T., Kulathu, Yogesh, Alpi, Arno F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393609/
https://www.ncbi.nlm.nih.gov/pubmed/30587576
http://dx.doi.org/10.1074/jbc.RA118.005861

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