Return of secondary findings in genomic sequencing: Military implications

BACKGROUND: Genomic sequencing has become a widely used tool in clinical and research settings in both civilian and military healthcare systems. METHODS: In this paper, we consider potential military‐specific implications of returning genomic sequencing secondary findings to ensure the proper protec...

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Autores principales: Hellwig, Lydia D., Turner, Clesson, Manolio, Teri A., Haigney, Mark, James, Cynthia A., Murray, Brittney, Szpisjak, Dale F., Muldoon, Sheila, Estrada‐Veras, Juvianee, Krokosky, Alyson, De Castro, Mauricio J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Special Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393684/
https://www.ncbi.nlm.nih.gov/pubmed/30415494
http://dx.doi.org/10.1002/mgg3.483
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author Hellwig, Lydia D.
Turner, Clesson
Manolio, Teri A.
Haigney, Mark
James, Cynthia A.
Murray, Brittney
Szpisjak, Dale F.
Muldoon, Sheila
Estrada‐Veras, Juvianee
Krokosky, Alyson
De Castro, Mauricio J.
author_facet Hellwig, Lydia D.
Turner, Clesson
Manolio, Teri A.
Haigney, Mark
James, Cynthia A.
Murray, Brittney
Szpisjak, Dale F.
Muldoon, Sheila
Estrada‐Veras, Juvianee
Krokosky, Alyson
De Castro, Mauricio J.
author_sort Hellwig, Lydia D.
collection PubMed
description BACKGROUND: Genomic sequencing has become a widely used tool in clinical and research settings in both civilian and military healthcare systems. METHODS: In this paper, we consider potential military‐specific implications of returning genomic sequencing secondary findings to ensure the proper protections, policies, and processes are in place for the use of this information. RESULTS: We specifically use two examples to highlight potential military implications of the return of secondary findings. CONCLUSION: Clinicians and researchers are strongly encouraged to consider the military implications of the return of results for informed consent of service members or their families undergoing clinical or research genomic sequencing.
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spelling pubmed-63936842019-03-08 Return of secondary findings in genomic sequencing: Military implications Hellwig, Lydia D. Turner, Clesson Manolio, Teri A. Haigney, Mark James, Cynthia A. Murray, Brittney Szpisjak, Dale F. Muldoon, Sheila Estrada‐Veras, Juvianee Krokosky, Alyson De Castro, Mauricio J. Mol Genet Genomic Med Special Article BACKGROUND: Genomic sequencing has become a widely used tool in clinical and research settings in both civilian and military healthcare systems. METHODS: In this paper, we consider potential military‐specific implications of returning genomic sequencing secondary findings to ensure the proper protections, policies, and processes are in place for the use of this information. RESULTS: We specifically use two examples to highlight potential military implications of the return of secondary findings. CONCLUSION: Clinicians and researchers are strongly encouraged to consider the military implications of the return of results for informed consent of service members or their families undergoing clinical or research genomic sequencing. John Wiley and Sons Inc. 2018-11-10 /pmc/articles/PMC6393684/ /pubmed/30415494 http://dx.doi.org/10.1002/mgg3.483 Text en © 2018 The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. Molecular Genetics & Genomic Medicine published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Special Article
Hellwig, Lydia D.
Turner, Clesson
Manolio, Teri A.
Haigney, Mark
James, Cynthia A.
Murray, Brittney
Szpisjak, Dale F.
Muldoon, Sheila
Estrada‐Veras, Juvianee
Krokosky, Alyson
De Castro, Mauricio J.
Return of secondary findings in genomic sequencing: Military implications
title Return of secondary findings in genomic sequencing: Military implications
title_full Return of secondary findings in genomic sequencing: Military implications
title_fullStr Return of secondary findings in genomic sequencing: Military implications
title_full_unstemmed Return of secondary findings in genomic sequencing: Military implications
title_short Return of secondary findings in genomic sequencing: Military implications
title_sort return of secondary findings in genomic sequencing: military implications
topic Special Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393684/
https://www.ncbi.nlm.nih.gov/pubmed/30415494
http://dx.doi.org/10.1002/mgg3.483
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