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Initiating DNA replication: a matter of prime importance

It has been known for decades that the principal replicative DNA polymerases that effect genome replication are incapable of starting DNA synthesis de novo. Rather, they require a 3′-OH group from which to extend a DNA chain. Cellular DNA replication systems exploit a dedicated, limited processivity...

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Detalles Bibliográficos
Autor principal: Bell, Stephen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393858/
https://www.ncbi.nlm.nih.gov/pubmed/30647143
http://dx.doi.org/10.1042/BST20180627

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