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Killing Two Angry Birds with One Stone: Autophagy Activation by Inhibiting Calpains in Neurodegenerative Diseases and Beyond

Proteolytic machineries execute vital cellular functions and their disturbances are implicated in diverse medical conditions, including neurodegenerative diseases. Interestingly, calpains, a class of Ca(2+)-dependent regulatory proteases, can modulate the degradational system of autophagy by cleavin...

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Detalles Bibliográficos
Autores principales:	Weber, Jonasz Jeremiasz, Pereira Sena, Priscila, Singer, Elisabeth, Nguyen, Huu Phuc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393885/ https://www.ncbi.nlm.nih.gov/pubmed/30895192 http://dx.doi.org/10.1155/2019/4741252

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