An LC-MS/MS Method for Simultaneous Determination of the Toxic and Active Components of Cortex Periplocae in Rat Plasma and Application to a Pharmacokinetic Study

A sensitive and simple liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated to simultaneously determine the toxic and other active components including isovanillin, scopoletin, periplocin, periplogenin, and periplocymarin after oral administration of cortex pe...

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Detalles Bibliográficos
Autores principales: Li, Zhen, Li, Yang, Li, Jin, Liu, Rui, Hao, Jia, He, Jun, Chang, Yan-xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393897/
https://www.ncbi.nlm.nih.gov/pubmed/30894874
http://dx.doi.org/10.1155/2019/1639619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393897/
https://www.ncbi.nlm.nih.gov/pubmed/30894874
http://dx.doi.org/10.1155/2019/1639619

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