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A Case Report of Melanoma as Acute Mastoiditis in a 10-Month-Old Female Child

We present a rare case of transplacental-transmitted maternal melanoma to the placenta and foetus during the pregnancy of a 34-year-old woman. She was diagnosed with a melanoma at the age of 25, for which she was treated with chemotherapy. During her pregnancy, she presented with a recurrence of the...

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Autores principales: Chrysouli, Konstantina, Tsakanikos, Michael, Stamataki, Sofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393903/
https://www.ncbi.nlm.nih.gov/pubmed/30906611
http://dx.doi.org/10.1155/2019/9641945
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author Chrysouli, Konstantina
Tsakanikos, Michael
Stamataki, Sofia
author_facet Chrysouli, Konstantina
Tsakanikos, Michael
Stamataki, Sofia
author_sort Chrysouli, Konstantina
collection PubMed
description We present a rare case of transplacental-transmitted maternal melanoma to the placenta and foetus during the pregnancy of a 34-year-old woman. She was diagnosed with a melanoma at the age of 25, for which she was treated with chemotherapy. During her pregnancy, she presented with a recurrence of the disease and died 3 months after delivery. The 10-month-old female child presented with a recurrent retroauricular oedema on the left side. A trephination of mastoid apophysis followed. Multiple fragments of dark-coloured tissue were sent for histological examination, and the immunophenotype showed a melanocytic tumour in the mastoid. A full radiological assessment showed no sign of metastasis. The child remained without treatment. Complete remission of bone metastatic lesion has been confirmed by follow-up; now, the child is 4 years old, alive, and without evidence of disease.
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spelling pubmed-63939032019-03-24 A Case Report of Melanoma as Acute Mastoiditis in a 10-Month-Old Female Child Chrysouli, Konstantina Tsakanikos, Michael Stamataki, Sofia Case Rep Otolaryngol Case Report We present a rare case of transplacental-transmitted maternal melanoma to the placenta and foetus during the pregnancy of a 34-year-old woman. She was diagnosed with a melanoma at the age of 25, for which she was treated with chemotherapy. During her pregnancy, she presented with a recurrence of the disease and died 3 months after delivery. The 10-month-old female child presented with a recurrent retroauricular oedema on the left side. A trephination of mastoid apophysis followed. Multiple fragments of dark-coloured tissue were sent for histological examination, and the immunophenotype showed a melanocytic tumour in the mastoid. A full radiological assessment showed no sign of metastasis. The child remained without treatment. Complete remission of bone metastatic lesion has been confirmed by follow-up; now, the child is 4 years old, alive, and without evidence of disease. Hindawi 2019-02-14 /pmc/articles/PMC6393903/ /pubmed/30906611 http://dx.doi.org/10.1155/2019/9641945 Text en Copyright © 2019 Konstantina Chrysouli et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Chrysouli, Konstantina
Tsakanikos, Michael
Stamataki, Sofia
A Case Report of Melanoma as Acute Mastoiditis in a 10-Month-Old Female Child
title A Case Report of Melanoma as Acute Mastoiditis in a 10-Month-Old Female Child
title_full A Case Report of Melanoma as Acute Mastoiditis in a 10-Month-Old Female Child
title_fullStr A Case Report of Melanoma as Acute Mastoiditis in a 10-Month-Old Female Child
title_full_unstemmed A Case Report of Melanoma as Acute Mastoiditis in a 10-Month-Old Female Child
title_short A Case Report of Melanoma as Acute Mastoiditis in a 10-Month-Old Female Child
title_sort case report of melanoma as acute mastoiditis in a 10-month-old female child
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393903/
https://www.ncbi.nlm.nih.gov/pubmed/30906611
http://dx.doi.org/10.1155/2019/9641945
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