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Computer-aided assessment of the extra-cellular matrix during pancreatic carcinogenesis: a pilot study
BACKGROUND: A hallmark of pancreatic ductal adenocarcinoma is the desmoplastic reaction, but its impact on the tumor behavior remains controversial. Our aim was to introduce a computer -aided method to precisely quantify the amount of pancreatic collagenic extra-cellular matrix, its spatial distribu...
Autores principales: | Grizzi, Fabio, Fiorino, Sirio, Qehajaj, Dorina, Fornelli, Adele, Russo, Carlo, de Biase, Dario, Masetti, Michele, Mastrangelo, Laura, Zanello, Matteo, Lombardi, Raffaele, Domanico, Andrea, Accogli, Esterita, Tura, Andrea, Mirandola, Leonardo, Chiriva-Internati, Maurizio, Bresalier, Robert S., Jovine, Elio, Leandri, Paolo, Di Tommaso, Luca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393991/ https://www.ncbi.nlm.nih.gov/pubmed/30819202 http://dx.doi.org/10.1186/s12967-019-1817-3 |
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