Cargando…

Deprivation of the Periplasmic Chaperone SurA Reduces Virulence and Restores Antibiotic Susceptibility of Multidrug-Resistant Pseudomonas aeruginosa

Pseudomonas aeruginosa is one of the main causative agents of nosocomial infections and the spread of multidrug-resistant strains is rising. Therefore, novel strategies for therapy are urgently required. The outer membrane composition of Gram-negative pathogens and especially of Pa restricts the eff...

Descripción completa

Detalles Bibliográficos
Autores principales:	Klein, Kristina, Sonnabend, Michael S., Frank, Lisa, Leibiger, Karolin, Franz-Wachtel, Mirita, Macek, Boris, Trunk, Thomas, Leo, Jack C., Autenrieth, Ingo B., Schütz, Monika, Bohn, Erwin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394205/ https://www.ncbi.nlm.nih.gov/pubmed/30846971 http://dx.doi.org/10.3389/fmicb.2019.00100

Ejemplares similares

An Unprecedented Tolerance to Deletion of the Periplasmic Chaperones SurA, Skp, and DegP in the Nosocomial Pathogen Acinetobacter baumannii
por: Birkle, Karolin, et al.
Publicado: (2022)

Interaction of the periplasmic chaperone SurA with the inner membrane protein secretion (SEC) machinery
por: Troman, Lucy, et al.
Publicado: (2023)

Dynamic interplay between the periplasmic chaperone SurA and the BAM complex in outer membrane protein folding
por: Schiffrin, Bob, et al.
Publicado: (2022)

Identifying components required for OMP biogenesis as novel targets for antiinfective drugs
por: Weirich, Johanna, et al.
Publicado: (2017)

The Activity and Specificity of the Outer Membrane Protein Chaperone SurA Are Modulated by a Proline Isomerase Domain
por: Ricci, Dante P., et al.
Publicado: (2013)

Chaperones Skp and SurA dynamically expand unfolded OmpX and synergistically disassemble oligomeric aggregates
por: Chamachi, Neharika, et al.
Publicado: (2022)

Inter-domain dynamics in the chaperone SurA and multi-site binding to its outer membrane protein clients
por: Calabrese, Antonio N., et al.
Publicado: (2020)

Structural characterization of PaFkbA: A periplasmic chaperone from Pseudomonas aeruginosa
por: Huang, Qin, et al.
Publicado: (2021)

The periplasmic chaperone Skp prevents misfolding of the secretory lipase A from Pseudomonas aeruginosa
por: Papadopoulos, Athanasios, et al.
Publicado: (2022)

Stress-Responsive Periplasmic Chaperones in Bacteria
por: Kim, Hyunhee, et al.
Publicado: (2021)

Identification of Drug Resistance Determinants in a Clinical Isolate of Pseudomonas aeruginosa by High-Density Transposon Mutagenesis
por: Sonnabend, Michael S., et al.
Publicado: (2020)

Components of SurA Required for Outer Membrane Biogenesis in Uropathogenic Escherichia coli
por: Watts, Kristin M., et al.
Publicado: (2008)

A network of cytosolic (co)chaperones promotes the biogenesis of mitochondrial signal-anchored outer membrane proteins
por: Drwesh, Layla, et al.
Publicado: (2022)

Cytosolic Hsp70 and Hsp40 chaperones enable the biogenesis of mitochondrial β-barrel proteins
por: Jores, Tobias, et al.
Publicado: (2018)

PpiD is a player in the network of periplasmic chaperones in Escherichia coli
por: Matern, Yvonne, et al.
Publicado: (2010)

Periplasmic chaperone FkpA is essential for imported colicin M toxicity
por: Hullmann, Julia, et al.
Publicado: (2008)

Direct Observation of the Uptake of Outer Membrane Proteins by the Periplasmic Chaperone Skp
por: Lyu, Zhi-Xin, et al.
Publicado: (2012)

Characterization of a periplasmic nitrate reductase in complex with its biosynthetic chaperone
por: Dow, Jennifer M., et al.
Publicado: (2013)

STUDIES ON MRTASANJIVANI SURA
por: Alam, Muzaffer, et al.
Publicado: (1989)

Substitutions in SurA and BamA Lead to Reduced Susceptibility to Broad Range Antibiotics in Gonococci
por: Bodoev, Ivan, et al.
Publicado: (2021)

Formation of Fibrils by the Periplasmic Molecular Chaperone HdeB from Escherichia coli
por: Nakata, Yui, et al.
Publicado: (2022)

SurA-like and Skp-like Proteins as Important Virulence Determinants of the Gram Negative Bacterial Pathogens
por: Figaj, Donata, et al.
Publicado: (2022)

Periplasmic expression of soluble single chain T cell receptors is rescued by the chaperone FkpA
por: Gunnarsen, Kristin S, et al.
Publicado: (2010)

Dissecting the Effects of Periplasmic Chaperones on the In Vitro Folding of the Outer Membrane Protein PagP
por: McMorran, Lindsay M., et al.
Publicado: (2013)

Chaperone-mediated native folding of a β-scorpion toxin in the periplasm of Escherichia coli()
por: O'Reilly, A.O., et al.
Publicado: (2014)

Proteasomal turnover of the RhoGAP tumor suppressor DLC1 is regulated by HECTD1 and USP7
por: Frey, Yannick, et al.
Publicado: (2022)

Yersinia enterocolitica Targets Cells of the Innate and Adaptive Immune System by Injection of Yops in a Mouse Infection Model
por: Köberle, Martin, et al.
Publicado: (2009)

A flagellum-specific chaperone facilitates assembly of the core type III export apparatus of the bacterial flagellum
por: Fabiani, Florian D., et al.
Publicado: (2017)

Effects of Periplasmic Chaperones and Membrane Thickness on BamA-Catalyzed Outer-Membrane Protein Folding
por: Schiffrin, Bob, et al.
Publicado: (2017)

The adaptability of the ion-binding site by the Ag(I)/Cu(I) periplasmic chaperone SilF
por: Lithgo, Ryan M., et al.
Publicado: (2023)

The Periplasmic Protein TolB as a Potential Drug Target in Pseudomonas aeruginosa
por: Lo Sciuto, Alessandra, et al.
Publicado: (2014)

3rd CEBAF/SURA Summer Workshop
por: Gross, F, et al.
Publicado: (1986)

4th CEBAF/SURA Summer Workshop
por: Gross, F, et al.
Publicado: (1987)

1st CEBAF/SURA Summer Workshop
por: Gross, F, et al.
Publicado: (1984)

2nd CEBAF/SURA Summer Workshop
por: Crannell, Hall, et al.
Publicado: (1985)

Inward and outward currents of native and cloned K(ATP) channels (Kir6.2/SUR1) share single-channel kinetic properties
por: Bränström, Robert, et al.
Publicado: (2022)

Forced IFIT-2 expression represses LPS induced TNF-alpha expression at posttranscriptional levels
por: Berchtold, Susanne, et al.
Publicado: (2008)

YgfB increases β-lactam resistance in Pseudomonas aeruginosa by counteracting AlpA-mediated ampDh3 expression
por: Eggers, Ole, et al.
Publicado: (2023)

A Computational Model of Bacterial Population Dynamics in Gastrointestinal Yersinia enterocolitica Infections in Mice
por: Geißert, Janina K., et al.
Publicado: (2022)

The neuropeptide complement of the marine annelid Platynereis dumerilii
por: Conzelmann, Markus, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_u94kj7k5anc5n6ni3fvmgelbvj