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Infection-Induced Resistance to Experimental Cerebral Malaria Is Dependent Upon Secreted Antibody-Mediated Inhibition of Pathogenic CD8(+) T Cell Responses

Cerebral malaria (CM) is one of the most severe complications of Plasmodium falciparum infection. There is evidence that repeated parasite exposure promotes resistance against CM. However, the immunological basis of this infection-induced resistance remains poorly understood. Here, utilizing the Pla...

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Detalles Bibliográficos
Autores principales: Shaw, Tovah N., Inkson, Colette A., Villegas-Mendez, Ana, Pattinson, David J., Strangward, Patrick, Else, Kathryn J., Draper, Simon J., Zeef, Leo A. H., Couper, Kevin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394254/
https://www.ncbi.nlm.nih.gov/pubmed/30846985
http://dx.doi.org/10.3389/fimmu.2019.00248