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Infection-Induced Resistance to Experimental Cerebral Malaria Is Dependent Upon Secreted Antibody-Mediated Inhibition of Pathogenic CD8(+) T Cell Responses
Cerebral malaria (CM) is one of the most severe complications of Plasmodium falciparum infection. There is evidence that repeated parasite exposure promotes resistance against CM. However, the immunological basis of this infection-induced resistance remains poorly understood. Here, utilizing the Pla...
Autores principales: | Shaw, Tovah N., Inkson, Colette A., Villegas-Mendez, Ana, Pattinson, David J., Strangward, Patrick, Else, Kathryn J., Draper, Simon J., Zeef, Leo A. H., Couper, Kevin N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394254/ https://www.ncbi.nlm.nih.gov/pubmed/30846985 http://dx.doi.org/10.3389/fimmu.2019.00248 |
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