Prophylactic effect of scopolamine butylbromide, a competitive antagonist of muscarinic acetylcholine receptor, on irinotecan-related cholinergic syndrome

BACKGROUND/AIM: Cholinergic syndrome frequently occurs within the first 24 h after irinotecan injection. We evaluated the prophylactic effect of scopolamine butylbromide on irinotecan-related cholinergic syndrome. PATIENTS AND METHODS: Fifty-nine patients who received irinotecan-based regimens at ou...

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Detalles Bibliográficos
Autores principales: Iihara, Hirotoshi, Fujii, Hironori, Yoshimi, Chiaki, Kobayashi, Ryo, Matsuhashi, Nobuhisa, Takahashi, Takao, Yoshida, Kazuhiro, Suzuki, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394464/
https://www.ncbi.nlm.nih.gov/pubmed/30564875
http://dx.doi.org/10.1007/s00280-018-3736-z

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