A phase I study of single-agent BEZ235 special delivery system sachet in Japanese patients with advanced solid tumors

PURPOSE: BEZ235 is a dual kinase inhibitor of phosphatidylinositol 3-kinase (PI3K) and mammalian target of rapamycin, which are key components of the PI3K pathway. This was an open-label, multicenter, dose-escalation, phase I study of single-agent BEZ235 in Japanese oncology patients to determine th...

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Detalles Bibliográficos
Autores principales: Toyoda, Masanori, Watanabe, Koichiro, Amagasaki, Taro, Natsume, Kazuto, Takeuchi, Hiromi, Quadt, Cornelia, Shirao, Kuniaki, Minami, Hironobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394493/
https://www.ncbi.nlm.nih.gov/pubmed/30446785
http://dx.doi.org/10.1007/s00280-018-3725-2

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