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Frequent discordance in PD-1 and PD-L1 expression between primary breast tumors and their matched distant metastases

Programmed death-1 (PD-1) is an immune checkpoint that is able to inhibit the immune system by binding to its ligand programmed death-ligand 1 (PD-L1). In many cancer types, among which breast cancer, prognostic and/or predictive values have been suggested for both PD-1 and PD-L1. Previous research...

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Detalles Bibliográficos
Autores principales: Manson, Quirine F., Schrijver, Willemijne A. M. E., ter Hoeve, Natalie D., Moelans, Cathy B., van Diest, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394593/
https://www.ncbi.nlm.nih.gov/pubmed/30547271
http://dx.doi.org/10.1007/s10585-018-9950-6