Cargando…

Use of 3D imaging for providing insights into high-order structure of mitotic chromosomes

The high-order structure of metaphase chromosomes remains still under investigation, especially the 30-nm structure that is still controversial. Advanced 3D imaging has provided useful information for our understanding of this detailed structure. It is evident that new technologies together with imp...

Descripción completa

Detalles Bibliográficos
Autores principales: Yusuf, Mohammed, Kaneyoshi, Kohei, Fukui, Kiichi, Robinson, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394650/
https://www.ncbi.nlm.nih.gov/pubmed/30175387
http://dx.doi.org/10.1007/s00412-018-0678-5
_version_ 1783398939483963392
author Yusuf, Mohammed
Kaneyoshi, Kohei
Fukui, Kiichi
Robinson, Ian
author_facet Yusuf, Mohammed
Kaneyoshi, Kohei
Fukui, Kiichi
Robinson, Ian
author_sort Yusuf, Mohammed
collection PubMed
description The high-order structure of metaphase chromosomes remains still under investigation, especially the 30-nm structure that is still controversial. Advanced 3D imaging has provided useful information for our understanding of this detailed structure. It is evident that new technologies together with improved sample preparations and image analyses should be adequately combined. This mini review highlights 3D imaging used for chromosome analysis so far with future imaging directions also highlighted.
format Online
Article
Text
id pubmed-6394650
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Springer Berlin Heidelberg
record_format MEDLINE/PubMed
spelling pubmed-63946502019-03-15 Use of 3D imaging for providing insights into high-order structure of mitotic chromosomes Yusuf, Mohammed Kaneyoshi, Kohei Fukui, Kiichi Robinson, Ian Chromosoma Mini-Review The high-order structure of metaphase chromosomes remains still under investigation, especially the 30-nm structure that is still controversial. Advanced 3D imaging has provided useful information for our understanding of this detailed structure. It is evident that new technologies together with improved sample preparations and image analyses should be adequately combined. This mini review highlights 3D imaging used for chromosome analysis so far with future imaging directions also highlighted. Springer Berlin Heidelberg 2018-09-03 2019 /pmc/articles/PMC6394650/ /pubmed/30175387 http://dx.doi.org/10.1007/s00412-018-0678-5 Text en © The Author(s) 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Mini-Review
Yusuf, Mohammed
Kaneyoshi, Kohei
Fukui, Kiichi
Robinson, Ian
Use of 3D imaging for providing insights into high-order structure of mitotic chromosomes
title Use of 3D imaging for providing insights into high-order structure of mitotic chromosomes
title_full Use of 3D imaging for providing insights into high-order structure of mitotic chromosomes
title_fullStr Use of 3D imaging for providing insights into high-order structure of mitotic chromosomes
title_full_unstemmed Use of 3D imaging for providing insights into high-order structure of mitotic chromosomes
title_short Use of 3D imaging for providing insights into high-order structure of mitotic chromosomes
title_sort use of 3d imaging for providing insights into high-order structure of mitotic chromosomes
topic Mini-Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394650/
https://www.ncbi.nlm.nih.gov/pubmed/30175387
http://dx.doi.org/10.1007/s00412-018-0678-5
work_keys_str_mv AT yusufmohammed useof3dimagingforprovidinginsightsintohighorderstructureofmitoticchromosomes
AT kaneyoshikohei useof3dimagingforprovidinginsightsintohighorderstructureofmitoticchromosomes
AT fukuikiichi useof3dimagingforprovidinginsightsintohighorderstructureofmitoticchromosomes
AT robinsonian useof3dimagingforprovidinginsightsintohighorderstructureofmitoticchromosomes