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Use of 3D imaging for providing insights into high-order structure of mitotic chromosomes
The high-order structure of metaphase chromosomes remains still under investigation, especially the 30-nm structure that is still controversial. Advanced 3D imaging has provided useful information for our understanding of this detailed structure. It is evident that new technologies together with imp...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394650/ https://www.ncbi.nlm.nih.gov/pubmed/30175387 http://dx.doi.org/10.1007/s00412-018-0678-5 |
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author | Yusuf, Mohammed Kaneyoshi, Kohei Fukui, Kiichi Robinson, Ian |
author_facet | Yusuf, Mohammed Kaneyoshi, Kohei Fukui, Kiichi Robinson, Ian |
author_sort | Yusuf, Mohammed |
collection | PubMed |
description | The high-order structure of metaphase chromosomes remains still under investigation, especially the 30-nm structure that is still controversial. Advanced 3D imaging has provided useful information for our understanding of this detailed structure. It is evident that new technologies together with improved sample preparations and image analyses should be adequately combined. This mini review highlights 3D imaging used for chromosome analysis so far with future imaging directions also highlighted. |
format | Online Article Text |
id | pubmed-6394650 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-63946502019-03-15 Use of 3D imaging for providing insights into high-order structure of mitotic chromosomes Yusuf, Mohammed Kaneyoshi, Kohei Fukui, Kiichi Robinson, Ian Chromosoma Mini-Review The high-order structure of metaphase chromosomes remains still under investigation, especially the 30-nm structure that is still controversial. Advanced 3D imaging has provided useful information for our understanding of this detailed structure. It is evident that new technologies together with improved sample preparations and image analyses should be adequately combined. This mini review highlights 3D imaging used for chromosome analysis so far with future imaging directions also highlighted. Springer Berlin Heidelberg 2018-09-03 2019 /pmc/articles/PMC6394650/ /pubmed/30175387 http://dx.doi.org/10.1007/s00412-018-0678-5 Text en © The Author(s) 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Mini-Review Yusuf, Mohammed Kaneyoshi, Kohei Fukui, Kiichi Robinson, Ian Use of 3D imaging for providing insights into high-order structure of mitotic chromosomes |
title | Use of 3D imaging for providing insights into high-order structure of mitotic chromosomes |
title_full | Use of 3D imaging for providing insights into high-order structure of mitotic chromosomes |
title_fullStr | Use of 3D imaging for providing insights into high-order structure of mitotic chromosomes |
title_full_unstemmed | Use of 3D imaging for providing insights into high-order structure of mitotic chromosomes |
title_short | Use of 3D imaging for providing insights into high-order structure of mitotic chromosomes |
title_sort | use of 3d imaging for providing insights into high-order structure of mitotic chromosomes |
topic | Mini-Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394650/ https://www.ncbi.nlm.nih.gov/pubmed/30175387 http://dx.doi.org/10.1007/s00412-018-0678-5 |
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