Inhibition of ghrelin-induced feeding in rats by pretreatment with a novel dual orexin receptor antagonist

Orexin-A and -B, and ghrelin are potent orexigenic peptides. The effects of ACT462206, a novel dual orexin receptor antagonist (DORA), on ghrelin-induced feeding were examined in adult male Wistar rats. Hyperphagia induced by the intracerebroventricular (icv) administration of ghrelin was significan...

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Detalles Bibliográficos
Autores principales: So, Mariko, Hashimoto, Hirofumi, Saito, Reiko, Yamamoto, Yukiyo, Motojima, Yasuhito, Ueno, Hiromichi, Sonoda, Satomi, Yoshimura, Mitsuhiro, Maruyama, Takashi, Kusuhara, Koichi, Ueta, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394659/
https://www.ncbi.nlm.nih.gov/pubmed/28054308
http://dx.doi.org/10.1007/s12576-016-0517-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394659/
https://www.ncbi.nlm.nih.gov/pubmed/28054308
http://dx.doi.org/10.1007/s12576-016-0517-5

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