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Inhibition of ghrelin-induced feeding in rats by pretreatment with a novel dual orexin receptor antagonist

Orexin-A and -B, and ghrelin are potent orexigenic peptides. The effects of ACT462206, a novel dual orexin receptor antagonist (DORA), on ghrelin-induced feeding were examined in adult male Wistar rats. Hyperphagia induced by the intracerebroventricular (icv) administration of ghrelin was significan...

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Detalles Bibliográficos
Autores principales:	So, Mariko, Hashimoto, Hirofumi, Saito, Reiko, Yamamoto, Yukiyo, Motojima, Yasuhito, Ueno, Hiromichi, Sonoda, Satomi, Yoshimura, Mitsuhiro, Maruyama, Takashi, Kusuhara, Koichi, Ueta, Yoichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Japan 2017
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394659/ https://www.ncbi.nlm.nih.gov/pubmed/28054308 http://dx.doi.org/10.1007/s12576-016-0517-5

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