The Septate Junction Protein Tsp2A Restricts Intestinal Stem Cell Activity via Endocytic Regulation of aPKC and Hippo Signaling

Hippo signaling and the activity of its transcriptional coactivator, Yorkie (Yki), are conserved and crucial regulators of tissue homeostasis. In the Drosophila midgut, after tissue damage, Yki activity increases to stimulate stem cell proliferation, but how Yki activity is turned off once the tissu...

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Detalles Bibliográficos
Autores principales: Xu, Chiwei, Tang, Hong-Wen, Hung, Ruei-Jiun, Hu, Yanhui, Ni, Xiaochun, Housden, Benjamin E., Perrimon, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394833/
https://www.ncbi.nlm.nih.gov/pubmed/30650359
http://dx.doi.org/10.1016/j.celrep.2018.12.079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394833/
https://www.ncbi.nlm.nih.gov/pubmed/30650359
http://dx.doi.org/10.1016/j.celrep.2018.12.079

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