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Two isoforms of the RAC-specific guanine nucleotide exchange factor TIAM2 act oppositely on transmission ratio distortion by the mouse t-haplotype

Transmission ratio distortion (TRD) by the mouse t-haplotype, a variant region on chromosome 17, is a well-studied model of non-Mendelian inheritance. It is characterized by the high transmission ratio (up to 99%) of the t-haplotype from t/+ males to their offspring. TRD is achieved by the exquisite...

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Detalles Bibliográficos
Autores principales:	Charron, Yves, Willert, Jürgen, Lipkowitz, Bettina, Kusecek, Barica, Herrmann, Bernhard G., Bauer, Hermann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394906/ https://www.ncbi.nlm.nih.gov/pubmed/30817801 http://dx.doi.org/10.1371/journal.pgen.1007964

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