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Overcoming the pitfalls of automatic interpretation of whole genome sequencing data by online tools for the prediction of pyrazinamide resistance in Mycobacterium tuberculosis
OBJECTIVES: Automated online software tools that analyse whole genome sequencing (WGS) data without the need for bioinformatics expertise can motivate the implementation of WGS-based molecular drug susceptibility testing (DST) in routine diagnostic settings for tuberculosis (TB). Pyrazinamide (PZA)...
Autores principales: | Iwamoto, Tomotada, Murase, Yoshiro, Yoshida, Shiomi, Aono, Akio, Kuroda, Makoto, Sekizuka, Tsuyoshi, Yamashita, Akifumi, Kato, Kengo, Takii, Takemasa, Arikawa, Kentaro, Kato, Seiya, Mitarai, Satoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394917/ https://www.ncbi.nlm.nih.gov/pubmed/30817803 http://dx.doi.org/10.1371/journal.pone.0212798 |
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