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Perinatal outcomes of hypertensive disorders in pregnancy at a referral hospital, Southern Ethiopia

INTRODUCTION: Hypertensive Disorders in Pregnancy (HDP) complicate about 10% of pregnancies. It accounts to 50% of maternal death in sub-Saharan Africa and precedes 15% of perinatal deaths worldwide. In this study, we looked at the perinatal outcomes and factors associated with unfavorable perinatal...

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Autores principales: Asseffa, Netsanet Abera, Demissie, Birhanu Wondimeneh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394918/
https://www.ncbi.nlm.nih.gov/pubmed/30817780
http://dx.doi.org/10.1371/journal.pone.0213240
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author Asseffa, Netsanet Abera
Demissie, Birhanu Wondimeneh
author_facet Asseffa, Netsanet Abera
Demissie, Birhanu Wondimeneh
author_sort Asseffa, Netsanet Abera
collection PubMed
description INTRODUCTION: Hypertensive Disorders in Pregnancy (HDP) complicate about 10% of pregnancies. It accounts to 50% of maternal death in sub-Saharan Africa and precedes 15% of perinatal deaths worldwide. In this study, we looked at the perinatal outcomes and factors associated with unfavorable perinatal outcomes among women with hypertensive disorders in pregnancy at Wolaita Sodo teaching and referral hospital, southern Ethiopia. METHODS: A hospital based retrospective cross-sectional study design was employed among women hospitalized for hypertensive disorders in pregnancy. Socio-demographic, obstetrics, clinical laboratory, pregnancy complications and outcome were checked from patient records. Descriptive statistics were used to describe parameters collected from patient records. Bivariate and multiple logistic regressions were done to determine factors associated with unfavorable perinatal outcome. A P-value of less than 0.05 and 95% confidence interval not including 1 were considered statically significant. RESULTS: There were 168 (2.3%) cases of HDP of the total 7, 347 deliveries during the period of the study from January 2014-December 2016. 72.5% of mothers (72.5%) had vaginal delivery and 26.1% had Caesarean Section. This study revealed a perinatal mortality rate of 111.1 per 1000 live births. On bivariate logistic regression variables such as referral status, diastolic blood pressure, ANC use, types of HDP, fetal weight at birth, maternal complication and maternal outcome were found to be associated with unfavorable perinatal outcomes. On multiple logistic regression fetal weight at birth and maternal outcome were found to be an independent predictors of unfavorable perinatal outcome. CONCLUSION: Our study shows higher perinatal mortality in a tertiary hospital where emergency obstetric and newborn care is set and quality obstetric care is expected. However, tertiary facilities manage difficult cases which can explain the high PMR. But it is high which means there is enough room for improvement. Hence, the referral hospital and neighboring health facilities should give due emphasis for early detection and management of women with HDP.
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spelling pubmed-63949182019-03-08 Perinatal outcomes of hypertensive disorders in pregnancy at a referral hospital, Southern Ethiopia Asseffa, Netsanet Abera Demissie, Birhanu Wondimeneh PLoS One Research Article INTRODUCTION: Hypertensive Disorders in Pregnancy (HDP) complicate about 10% of pregnancies. It accounts to 50% of maternal death in sub-Saharan Africa and precedes 15% of perinatal deaths worldwide. In this study, we looked at the perinatal outcomes and factors associated with unfavorable perinatal outcomes among women with hypertensive disorders in pregnancy at Wolaita Sodo teaching and referral hospital, southern Ethiopia. METHODS: A hospital based retrospective cross-sectional study design was employed among women hospitalized for hypertensive disorders in pregnancy. Socio-demographic, obstetrics, clinical laboratory, pregnancy complications and outcome were checked from patient records. Descriptive statistics were used to describe parameters collected from patient records. Bivariate and multiple logistic regressions were done to determine factors associated with unfavorable perinatal outcome. A P-value of less than 0.05 and 95% confidence interval not including 1 were considered statically significant. RESULTS: There were 168 (2.3%) cases of HDP of the total 7, 347 deliveries during the period of the study from January 2014-December 2016. 72.5% of mothers (72.5%) had vaginal delivery and 26.1% had Caesarean Section. This study revealed a perinatal mortality rate of 111.1 per 1000 live births. On bivariate logistic regression variables such as referral status, diastolic blood pressure, ANC use, types of HDP, fetal weight at birth, maternal complication and maternal outcome were found to be associated with unfavorable perinatal outcomes. On multiple logistic regression fetal weight at birth and maternal outcome were found to be an independent predictors of unfavorable perinatal outcome. CONCLUSION: Our study shows higher perinatal mortality in a tertiary hospital where emergency obstetric and newborn care is set and quality obstetric care is expected. However, tertiary facilities manage difficult cases which can explain the high PMR. But it is high which means there is enough room for improvement. Hence, the referral hospital and neighboring health facilities should give due emphasis for early detection and management of women with HDP. Public Library of Science 2019-02-28 /pmc/articles/PMC6394918/ /pubmed/30817780 http://dx.doi.org/10.1371/journal.pone.0213240 Text en © 2019 Asseffa, Demissie http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Asseffa, Netsanet Abera
Demissie, Birhanu Wondimeneh
Perinatal outcomes of hypertensive disorders in pregnancy at a referral hospital, Southern Ethiopia
title Perinatal outcomes of hypertensive disorders in pregnancy at a referral hospital, Southern Ethiopia
title_full Perinatal outcomes of hypertensive disorders in pregnancy at a referral hospital, Southern Ethiopia
title_fullStr Perinatal outcomes of hypertensive disorders in pregnancy at a referral hospital, Southern Ethiopia
title_full_unstemmed Perinatal outcomes of hypertensive disorders in pregnancy at a referral hospital, Southern Ethiopia
title_short Perinatal outcomes of hypertensive disorders in pregnancy at a referral hospital, Southern Ethiopia
title_sort perinatal outcomes of hypertensive disorders in pregnancy at a referral hospital, southern ethiopia
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394918/
https://www.ncbi.nlm.nih.gov/pubmed/30817780
http://dx.doi.org/10.1371/journal.pone.0213240
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