Atypical Clinical Presentation of Crohn's Disease with Superior Mesenteric Vein Obstruction and Protein-losing Enteropathy

We herein report a 44-year-old man suffering from systemic edema due to protein-losing enteropathy (PLE) with superior mesenteric vein (SMV) obstruction and development of collateral veins, which subsequently proved to be a chronic result of thrombosis and a complication of Crohn's disease (CD)...

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Detalles Bibliográficos
Autores principales: Ito, Suguru, Higashiyama, Masaaki, Horiuchi, Kazuki, Mizoguchi, Akinori, Soga, Shigeyoshi, Tanemoto, Rina, Nishii, Shin, Terada, Hisato, Wada, Akinori, Sugihara, Nao, Hanawa, Yoshinori, Furuhashi, Hirotaka, Takajo, Takeshi, Shirakabe, Kazuhiko, Watanabe, Chikako, Komoto, Shunsuke, Tomita, Kengo, Nagao, Shigeaki, Shinozaki, Masami, Nakagawa, Akihiko, Kubota, Michio, Miyagishima, Daisuke, Gotoh, Nobuaki, Miura, Soichiro, Ueno, Hideki, Hokari, Ryota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395114/
https://www.ncbi.nlm.nih.gov/pubmed/30210116
http://dx.doi.org/10.2169/internalmedicine.1192-18
Descripción
Sumario:We herein report a 44-year-old man suffering from systemic edema due to protein-losing enteropathy (PLE) with superior mesenteric vein (SMV) obstruction and development of collateral veins, which subsequently proved to be a chronic result of thrombosis and a complication of Crohn's disease (CD). PLE was supposedly induced by both intestinal erosion and thrombosis-related lymphangiectasia, which was histologically proven in his surgically-resected ileal stenosis. Elemental diet and anti-TNFα agent improved his hypoalbuminemia after surgery. The rarity of the simultaneous coexistence of SMV obstruction and PLE and the precedence of these complications over typical abdominal symptoms of CD made the clinical course complex.

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