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Atypical Clinical Presentation of Crohn's Disease with Superior Mesenteric Vein Obstruction and Protein-losing Enteropathy
We herein report a 44-year-old man suffering from systemic edema due to protein-losing enteropathy (PLE) with superior mesenteric vein (SMV) obstruction and development of collateral veins, which subsequently proved to be a chronic result of thrombosis and a complication of Crohn's disease (CD)...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Japanese Society of Internal Medicine
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395114/ https://www.ncbi.nlm.nih.gov/pubmed/30210116 http://dx.doi.org/10.2169/internalmedicine.1192-18 |
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| author | Ito, Suguru Higashiyama, Masaaki Horiuchi, Kazuki Mizoguchi, Akinori Soga, Shigeyoshi Tanemoto, Rina Nishii, Shin Terada, Hisato Wada, Akinori Sugihara, Nao Hanawa, Yoshinori Furuhashi, Hirotaka Takajo, Takeshi Shirakabe, Kazuhiko Watanabe, Chikako Komoto, Shunsuke Tomita, Kengo Nagao, Shigeaki Shinozaki, Masami Nakagawa, Akihiko Kubota, Michio Miyagishima, Daisuke Gotoh, Nobuaki Miura, Soichiro Ueno, Hideki Hokari, Ryota |
| author_facet | Ito, Suguru Higashiyama, Masaaki Horiuchi, Kazuki Mizoguchi, Akinori Soga, Shigeyoshi Tanemoto, Rina Nishii, Shin Terada, Hisato Wada, Akinori Sugihara, Nao Hanawa, Yoshinori Furuhashi, Hirotaka Takajo, Takeshi Shirakabe, Kazuhiko Watanabe, Chikako Komoto, Shunsuke Tomita, Kengo Nagao, Shigeaki Shinozaki, Masami Nakagawa, Akihiko Kubota, Michio Miyagishima, Daisuke Gotoh, Nobuaki Miura, Soichiro Ueno, Hideki Hokari, Ryota |
| author_sort | Ito, Suguru |
| collection | PubMed |
| description | We herein report a 44-year-old man suffering from systemic edema due to protein-losing enteropathy (PLE) with superior mesenteric vein (SMV) obstruction and development of collateral veins, which subsequently proved to be a chronic result of thrombosis and a complication of Crohn's disease (CD). PLE was supposedly induced by both intestinal erosion and thrombosis-related lymphangiectasia, which was histologically proven in his surgically-resected ileal stenosis. Elemental diet and anti-TNFα agent improved his hypoalbuminemia after surgery. The rarity of the simultaneous coexistence of SMV obstruction and PLE and the precedence of these complications over typical abdominal symptoms of CD made the clinical course complex. |
| format | Online Article Text |
| id | pubmed-6395114 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2018 |
| publisher | The Japanese Society of Internal Medicine |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-63951142019-03-01 Atypical Clinical Presentation of Crohn's Disease with Superior Mesenteric Vein Obstruction and Protein-losing Enteropathy Ito, Suguru Higashiyama, Masaaki Horiuchi, Kazuki Mizoguchi, Akinori Soga, Shigeyoshi Tanemoto, Rina Nishii, Shin Terada, Hisato Wada, Akinori Sugihara, Nao Hanawa, Yoshinori Furuhashi, Hirotaka Takajo, Takeshi Shirakabe, Kazuhiko Watanabe, Chikako Komoto, Shunsuke Tomita, Kengo Nagao, Shigeaki Shinozaki, Masami Nakagawa, Akihiko Kubota, Michio Miyagishima, Daisuke Gotoh, Nobuaki Miura, Soichiro Ueno, Hideki Hokari, Ryota Intern Med Case Report We herein report a 44-year-old man suffering from systemic edema due to protein-losing enteropathy (PLE) with superior mesenteric vein (SMV) obstruction and development of collateral veins, which subsequently proved to be a chronic result of thrombosis and a complication of Crohn's disease (CD). PLE was supposedly induced by both intestinal erosion and thrombosis-related lymphangiectasia, which was histologically proven in his surgically-resected ileal stenosis. Elemental diet and anti-TNFα agent improved his hypoalbuminemia after surgery. The rarity of the simultaneous coexistence of SMV obstruction and PLE and the precedence of these complications over typical abdominal symptoms of CD made the clinical course complex. The Japanese Society of Internal Medicine 2018-09-12 2019-02-01 /pmc/articles/PMC6395114/ /pubmed/30210116 http://dx.doi.org/10.2169/internalmedicine.1192-18 Text en Copyright © 2019 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
| spellingShingle | Case Report Ito, Suguru Higashiyama, Masaaki Horiuchi, Kazuki Mizoguchi, Akinori Soga, Shigeyoshi Tanemoto, Rina Nishii, Shin Terada, Hisato Wada, Akinori Sugihara, Nao Hanawa, Yoshinori Furuhashi, Hirotaka Takajo, Takeshi Shirakabe, Kazuhiko Watanabe, Chikako Komoto, Shunsuke Tomita, Kengo Nagao, Shigeaki Shinozaki, Masami Nakagawa, Akihiko Kubota, Michio Miyagishima, Daisuke Gotoh, Nobuaki Miura, Soichiro Ueno, Hideki Hokari, Ryota Atypical Clinical Presentation of Crohn's Disease with Superior Mesenteric Vein Obstruction and Protein-losing Enteropathy |
| title | Atypical Clinical Presentation of Crohn's Disease with Superior Mesenteric Vein Obstruction and Protein-losing Enteropathy |
| title_full | Atypical Clinical Presentation of Crohn's Disease with Superior Mesenteric Vein Obstruction and Protein-losing Enteropathy |
| title_fullStr | Atypical Clinical Presentation of Crohn's Disease with Superior Mesenteric Vein Obstruction and Protein-losing Enteropathy |
| title_full_unstemmed | Atypical Clinical Presentation of Crohn's Disease with Superior Mesenteric Vein Obstruction and Protein-losing Enteropathy |
| title_short | Atypical Clinical Presentation of Crohn's Disease with Superior Mesenteric Vein Obstruction and Protein-losing Enteropathy |
| title_sort | atypical clinical presentation of crohn's disease with superior mesenteric vein obstruction and protein-losing enteropathy |
| topic | Case Report |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395114/ https://www.ncbi.nlm.nih.gov/pubmed/30210116 http://dx.doi.org/10.2169/internalmedicine.1192-18 |
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