Cargando…

ActivinA: a new leukemia-promoting factor conferring migratory advantage to B-cell precursor-acute lymphoblastic leukemic cells

B-cell precursor-acute lymphoblastic leukemia modulates the bone marrow (BM) niche to become leukemia-supporting and chemo-protective by reprogramming the stromal microenvironment. New therapies targeting the interplay between leukemia and stroma can help improve disease outcome. We identified Activ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Portale, Federica, Cricrì, Giulia, Bresolin, Silvia, Lupi, Monica, Gaspari, Stefania, Silvestri, Daniela, Russo, Barbara, Marino, Noemi, Ubezio, Paolo, Pagni, Fabio, Vergani, Patrizia, Kronnie, Geertruy Te, Valsecchi, Maria Grazia, Locatelli, Franco, Rizzari, Carmelo, Biondi, Andrea, Dander, Erica, D’Amico, Giovanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ferrata Storti Foundation 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395324/ https://www.ncbi.nlm.nih.gov/pubmed/30262563 http://dx.doi.org/10.3324/haematol.2018.188664

Ejemplares similares

PB1702: ACTIVINA MODULATES THE MICRORNA CARGO OF EXTRACELLULAR VESICLES RELEASED BY B-CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA (BCP-ALL) CELLS
por: Licari, Eugenia, et al.
Publicado: (2023)

ActivinA Induced SMAD1/5 Signaling in an iPSC Derived EC Model of Fibrodysplasia Ossificans Progressiva (FOP) Can Be Rescued by the Drug Candidate Saracatinib
por: Hildebrandt, Susanne, et al.
Publicado: (2021)

Array-Based Comparative Genomic Hybridization Analysis Reveals Chromosomal Copy Number Aberrations Associated with Clinical Outcome in Canine Diffuse Large B-Cell Lymphoma
por: Aricò, Arianna, et al.
Publicado: (2014)

Mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia: a report from the Italian AIEOP study group
por: Bresolin, Silvia, et al.
Publicado: (2016)

Deciphering KRAS and NRAS mutated clone dynamics in MLL-AF4 paediatric leukaemia by ultra deep sequencing analysis
por: Trentin, Luca, et al.
Publicado: (2016)

High expression of miR-125b-2 and SNORD116 noncoding RNA clusters characterize ERG-related B cell precursor acute lymphoblastic leukemia
por: Vendramini, Elena, et al.
Publicado: (2017)

Low PKCa expression within the MRD-HR stratum defines a new subgroup of childhood T-ALL with very poor outcome
por: Milani, Gloria, et al.
Publicado: (2014)

CirComPara: A Multi-Method Comparative Bioinformatics Pipeline to Detect and Study circRNAs from RNA-seq Data
por: Gaffo, Enrico, et al.
Publicado: (2017)

PAX5 fusion genes are frequent in poor risk childhood acute lymphoblastic leukaemia and can be targeted with BIBF1120
por: Fazio, Grazia, et al.
Publicado: (2022)

Epigenetic Silencing of TFPI-2 in Canine Diffuse Large B-Cell Lymphoma
por: Ferraresso, Serena, et al.
Publicado: (2014)

Activin B Regulates Adhesion, Invasiveness, and Migratory Activities in Oral Cancer: a Potential Biomarker for Metastasis
por: Kita, Akihiro, et al.
Publicado: (2017)

Mesenchymal stem cells from Shwachman–Diamond syndrome patients display normal functions and do not contribute to hematological defects
por: André, V, et al.
Publicado: (2012)

LCK over-expression drives STAT5 oncogenic signaling in PAX5 translocated BCP-ALL patients
por: Cazzaniga, Valeria, et al.
Publicado: (2015)

Definition and Prognostic Value of Ph-like and IKZF1plus Status in Children With Down Syndrome and B-cell Precursor Acute Lymphoblastic Leukemia
por: Palmi, Chiara, et al.
Publicado: (2023)

MLL rearrangements in pediatric acute lymphoblastic and myeloblastic leukemias: MLL specific and lineage specific signatures
por: Zangrando, Andrea, et al.
Publicado: (2009)

P374: THROMBOTIC EVENTS IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA: EXPERIENCE OF ITALIAN AIEOP CENTERS (2009-2017)
por: Mattera, Raffaele, et al.
Publicado: (2023)

Validation of flow cytometric phospho-STAT5 as a diagnostic tool for juvenile myelomonocytic leukemia
por: Hasegawa, D, et al.
Publicado: (2013)

FLT3-ITD in Children with Early T-cell Precursor (ETP) Acute Lymphoblastic Leukemia: Incidence and Potential Target for Monitoring Minimal Residual Disease (MRD)
por: Lo Nigro, Luca, et al.
Publicado: (2022)

Phase-related differences in egg production of the migratory locust regulated by differential oosorption through microRNA-34 targeting activinβ
por: Zhao, Lianfeng, et al.
Publicado: (2021)

AKR1C enzymes sustain therapy resistance in paediatric T-ALL
por: Bortolozzi, Roberta, et al.
Publicado: (2018)

Osteonecrosis in paediatric acute lymphoblastic leukaemia: Incidence, risk factors, radiological patterns and evolution in a single‐centre cohort
por: Brivio, Erica, et al.
Publicado: (2022)

NK Cell Reconstitution in Paediatric Leukemic Patients after T-Cell-Depleted HLA-Haploidentical Haematopoietic Stem Cell Transplantation Followed by the Reinfusion of iCasp9-Modified Donor T Cells
por: Stabile, Helena, et al.
Publicado: (2019)

ALL blasts drive primary mesenchymal stromal cells to increase asparagine availability during asparaginase treatment
por: Chiu, Martina, et al.
Publicado: (2021)

Activin eases asthma
por: Leslie, Mitch
Publicado: (2009)

Antibodies Covalently Immobilized on Actin Filaments for Fast Myosin Driven Analyte Transport
por: Kumar, Saroj, et al.
Publicado: (2012)

Dynamic Rendering of the Heterogeneous Cell Response to Anticancer Treatments
por: Falcetta, Francesca, et al.
Publicado: (2013)

Integrated experimental and simulation study of the response to sequential treatment with erlotinib and gemcitabine in pancreatic cancer
por: Ubezio, Paolo, et al.
Publicado: (2016)

Pentraxin 3 plasma levels at graft-versus-host disease onset predict disease severity and response to therapy in children given haematopoietic stem cell transplantation
por: Dander, Erica, et al.
Publicado: (2016)

The orphan ligand, activin C, signals through activin receptor-like kinase 7
por: Goebel, Erich J, et al.
Publicado: (2022)

Human and mouse activin genes: Divergent expression of activin A protein variants and identification of a novel heparan sulfate-binding domain in activin B
por: Billings, Paul C., et al.
Publicado: (2020)

Towards a Better Characterisation of Leukemic Cells in Chronic Lymphocytic Leukaemia: Cell-Size Heterogeneity Reflects Their Activation Status and Migratory Abilities
por: Manukyan, Gayane, et al.
Publicado: (2021)

Xnrs and Activin Regulate Distinct Genes during Xenopus Development: Activin Regulates Cell Division
por: Ramis, Joana M., et al.
Publicado: (2007)

An autocrine ActivinB mechanism drives TGFβ/Activin signaling in Group 3 medulloblastoma
por: Morabito, Morgane, et al.
Publicado: (2019)

Activin B and Activin C Have Opposing Effects on Prostate Cancer Progression and Cell Growth
por: Reader, Karen L., et al.
Publicado: (2022)

Simultaneous B and T cell acute lymphoblastic leukemias in zebrafish driven by transgenic MYC: implications for oncogenesis and lymphopoiesis
por: Borga, Chiara, et al.
Publicado: (2018)

Hematopoietic Stem Cell (HSC)-Independent Progenitors Are Susceptible to Mll-Af9-Induced Leukemic Transformation
por: Barone, Cristiana, et al.
Publicado: (2023)

Variations in activin receptor, inhibin/activin subunit and follistatin mRNAs in human prostate tumour tissues
por: Schaik, R H N van, et al.
Publicado: (2000)

Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects
Publicado: (1995)

New data on robustness of gene expression signatures in leukemia: comparison of three distinct total RNA preparation procedures
por: Campo Dell'Orto, Marta, et al.
Publicado: (2007)

Activin Biology After Lung Transplantation
por: Westall, Glen P., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_11uaeq47nfni186o6750l51vqp