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Clinical implications of subclonal TP53 mutations in acute myeloid leukemia

The role of subclonal TP53 mutations, defined by a variant allele frequency of <20%, has not been addressed in acute myeloid leukemia yet. We, therefore, analyzed their prognostic value in a cohort of 1,537 patients with newly diagnosed disease, prospectively treated within three trials of the “G...

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Detalles Bibliográficos
Autores principales:	Prochazka, Katharina T., Pregartner, Gudrun, Rücker, Frank G., Heitzer, Ellen, Pabst, Gabriel, Wölfler, Albert, Zebisch, Armin, Berghold, Andrea, Döhner, Konstanze, Sill, Heinz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ferrata Storti Foundation 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395341/ https://www.ncbi.nlm.nih.gov/pubmed/30309854 http://dx.doi.org/10.3324/haematol.2018.205013

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