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Omi/HtrA2 Protease Associated Cell Apoptosis Participates in Blood-Brain Barrier Dysfunction

Background: Omi/HtrA2 is a proapoptotic mitochondrial serine protease involved in caspase-dependent cell apoptosis, translocating from mitochondria to the cytosol after an apoptotic insult. Our previous study indicated pre-treatment with UCF-101, a specific inhibitor of Omi/HtrA2, could significantl...

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Detalles Bibliográficos
Autores principales:	Hu, Yueyu, Bi, Yong, Yao, Danhua, Wang, Pengfei, Li, Yousheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395387/ https://www.ncbi.nlm.nih.gov/pubmed/30853894 http://dx.doi.org/10.3389/fnmol.2019.00048

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