The Possible Role of Helicobacter pylori in Gastric Cancer and Its Management

Helicobacter pylori (HP) is a facultative anaerobic bacterium. HP is a normal flora having immuno-modulating properties. This bacterium is an example of a microorganism inducing gastric cancer. Its carcinogenicity depends on bacteria-host related factors. The proper understanding of the biology of H...

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Detalles Bibliográficos
Autores principales: Alfarouk, Khalid O., Bashir, Adil H. H., Aljarbou, Ahmed N., Ramadan, AbdelRahman M., Muddathir, Abdel Khalig, AlHoufie, Sari T. S., Hifny, Abdelhamid, Elhassan, Gamal O., Ibrahim, Muntaser E., Alqahtani, Saad S., AlSharari, Shakir D., Supuran, Claudiu T., Rauch, Cyril, Cardone, Rosa Angela, Reshkin, Stephan J., Fais, Stefano, Harguindey, Salvador
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395443/
https://www.ncbi.nlm.nih.gov/pubmed/30854333
http://dx.doi.org/10.3389/fonc.2019.00075
Descripción
Sumario:Helicobacter pylori (HP) is a facultative anaerobic bacterium. HP is a normal flora having immuno-modulating properties. This bacterium is an example of a microorganism inducing gastric cancer. Its carcinogenicity depends on bacteria-host related factors. The proper understanding of the biology of HP inducing gastric cancer offers the potential strategy in the managing of HP rather than eradicating it. In this article, we try to summarize the biology of HP-induced gastric cancer and discuss the current pharmacological approach to treat and prevent its carcinogenicity.

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