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The Possible Role of Helicobacter pylori in Gastric Cancer and Its Management
Helicobacter pylori (HP) is a facultative anaerobic bacterium. HP is a normal flora having immuno-modulating properties. This bacterium is an example of a microorganism inducing gastric cancer. Its carcinogenicity depends on bacteria-host related factors. The proper understanding of the biology of H...
| Autores principales: | , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395443/ https://www.ncbi.nlm.nih.gov/pubmed/30854333 http://dx.doi.org/10.3389/fonc.2019.00075 |
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| author | Alfarouk, Khalid O. Bashir, Adil H. H. Aljarbou, Ahmed N. Ramadan, AbdelRahman M. Muddathir, Abdel Khalig AlHoufie, Sari T. S. Hifny, Abdelhamid Elhassan, Gamal O. Ibrahim, Muntaser E. Alqahtani, Saad S. AlSharari, Shakir D. Supuran, Claudiu T. Rauch, Cyril Cardone, Rosa Angela Reshkin, Stephan J. Fais, Stefano Harguindey, Salvador |
| author_facet | Alfarouk, Khalid O. Bashir, Adil H. H. Aljarbou, Ahmed N. Ramadan, AbdelRahman M. Muddathir, Abdel Khalig AlHoufie, Sari T. S. Hifny, Abdelhamid Elhassan, Gamal O. Ibrahim, Muntaser E. Alqahtani, Saad S. AlSharari, Shakir D. Supuran, Claudiu T. Rauch, Cyril Cardone, Rosa Angela Reshkin, Stephan J. Fais, Stefano Harguindey, Salvador |
| author_sort | Alfarouk, Khalid O. |
| collection | PubMed |
| description | Helicobacter pylori (HP) is a facultative anaerobic bacterium. HP is a normal flora having immuno-modulating properties. This bacterium is an example of a microorganism inducing gastric cancer. Its carcinogenicity depends on bacteria-host related factors. The proper understanding of the biology of HP inducing gastric cancer offers the potential strategy in the managing of HP rather than eradicating it. In this article, we try to summarize the biology of HP-induced gastric cancer and discuss the current pharmacological approach to treat and prevent its carcinogenicity. |
| format | Online Article Text |
| id | pubmed-6395443 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2019 |
| publisher | Frontiers Media S.A. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-63954432019-03-08 The Possible Role of Helicobacter pylori in Gastric Cancer and Its Management Alfarouk, Khalid O. Bashir, Adil H. H. Aljarbou, Ahmed N. Ramadan, AbdelRahman M. Muddathir, Abdel Khalig AlHoufie, Sari T. S. Hifny, Abdelhamid Elhassan, Gamal O. Ibrahim, Muntaser E. Alqahtani, Saad S. AlSharari, Shakir D. Supuran, Claudiu T. Rauch, Cyril Cardone, Rosa Angela Reshkin, Stephan J. Fais, Stefano Harguindey, Salvador Front Oncol Oncology Helicobacter pylori (HP) is a facultative anaerobic bacterium. HP is a normal flora having immuno-modulating properties. This bacterium is an example of a microorganism inducing gastric cancer. Its carcinogenicity depends on bacteria-host related factors. The proper understanding of the biology of HP inducing gastric cancer offers the potential strategy in the managing of HP rather than eradicating it. In this article, we try to summarize the biology of HP-induced gastric cancer and discuss the current pharmacological approach to treat and prevent its carcinogenicity. Frontiers Media S.A. 2019-02-22 /pmc/articles/PMC6395443/ /pubmed/30854333 http://dx.doi.org/10.3389/fonc.2019.00075 Text en Copyright © 2019 Alfarouk, Bashir, Aljarbou, Ramadan, Muddathir, AlHoufie, Hifny, Elhassan, Ibrahim, Alqahtani, AlSharari, Supuran, Rauch, Cardone, Reshkin, Fais and Harguindey. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
| spellingShingle | Oncology Alfarouk, Khalid O. Bashir, Adil H. H. Aljarbou, Ahmed N. Ramadan, AbdelRahman M. Muddathir, Abdel Khalig AlHoufie, Sari T. S. Hifny, Abdelhamid Elhassan, Gamal O. Ibrahim, Muntaser E. Alqahtani, Saad S. AlSharari, Shakir D. Supuran, Claudiu T. Rauch, Cyril Cardone, Rosa Angela Reshkin, Stephan J. Fais, Stefano Harguindey, Salvador The Possible Role of Helicobacter pylori in Gastric Cancer and Its Management |
| title | The Possible Role of Helicobacter pylori in Gastric Cancer and Its Management |
| title_full | The Possible Role of Helicobacter pylori in Gastric Cancer and Its Management |
| title_fullStr | The Possible Role of Helicobacter pylori in Gastric Cancer and Its Management |
| title_full_unstemmed | The Possible Role of Helicobacter pylori in Gastric Cancer and Its Management |
| title_short | The Possible Role of Helicobacter pylori in Gastric Cancer and Its Management |
| title_sort | possible role of helicobacter pylori in gastric cancer and its management |
| topic | Oncology |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395443/ https://www.ncbi.nlm.nih.gov/pubmed/30854333 http://dx.doi.org/10.3389/fonc.2019.00075 |
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