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Cycling Quiescence in Temozolomide Resistant Glioblastoma Cells Is Partly Explained by microRNA-93 and -193-Mediated Decrease of Cyclin D
Glioblastoma multiforme (GBM) is a fatal malignancy of the central nervous system, commonly associated with chemoresistance. The alkylating agent Temozolomide (TMZ) is the front-line chemotherapeutic agent and has undergone intense studies on resistance. These studies reported on mismatch repair gen...
Autores principales: | Munoz, Jessian L., Walker, Nykia D., Mareedu, Satvik, Pamarthi, Sri Harika, Sinha, Garima, Greco, Steven J., Rameshwar, Pranela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395452/ https://www.ncbi.nlm.nih.gov/pubmed/30853911 http://dx.doi.org/10.3389/fphar.2019.00134 |
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