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Five-year Follow-up of Chronic Hepatitis B Patients Immunized by Nasal Route with the Therapeutic Vaccine HeberNasvac

A novel therapeutic vaccine for chronic hepatitis B (CHB) treatment comprising the recombinant hepatitis B surface (HBsAg) and nucleocapsid (HBcAg) antigens has been developed. Preclinical and clinical trials (CT) evidenced safety and immunogenicity in animal models as well as in phases I, II, and I...

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Detalles Bibliográficos
Autores principales: Fernández, Guillermo, L Sanchez, Ana, Jerez, Everardo, E Anillo, Luis, Freyre, Freya, A Aguiar, Jorge, Leon, Yamila, Cinza, Zurina, A Diaz, Pablo, Figueroa, Nelvis, Muzio, Verena, G Nieto, Gerardo, Lobaina, Yadira, Aguilar, Arístides, Penton, Eduardo, C Aguilar, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Jaypee Brothers Medical Publishers 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395482/
https://www.ncbi.nlm.nih.gov/pubmed/30828555
http://dx.doi.org/10.5005/jp-journals-10018-1279