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Five-year Follow-up of Chronic Hepatitis B Patients Immunized by Nasal Route with the Therapeutic Vaccine HeberNasvac
A novel therapeutic vaccine for chronic hepatitis B (CHB) treatment comprising the recombinant hepatitis B surface (HBsAg) and nucleocapsid (HBcAg) antigens has been developed. Preclinical and clinical trials (CT) evidenced safety and immunogenicity in animal models as well as in phases I, II, and I...
Autores principales: | Fernández, Guillermo, L Sanchez, Ana, Jerez, Everardo, E Anillo, Luis, Freyre, Freya, A Aguiar, Jorge, Leon, Yamila, Cinza, Zurina, A Diaz, Pablo, Figueroa, Nelvis, Muzio, Verena, G Nieto, Gerardo, Lobaina, Yadira, Aguilar, Arístides, Penton, Eduardo, C Aguilar, Julio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Jaypee Brothers Medical Publishers
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395482/ https://www.ncbi.nlm.nih.gov/pubmed/30828555 http://dx.doi.org/10.5005/jp-journals-10018-1279 |
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