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Overexpression of Aiolos promotes epithelial-mesenchymal transition and cancer stem cell-like properties in lung cancer cells

Aiolos/Ikaros family zinc finger 3 (IKZF3), a member of the Ikaros family of lymphocyte maturation-driving transcription factors, is highly expressed in hematopoietic malignancies. However, its role in epithelial-mesenchymal transition (EMT) and cancer stem cell (CSC)-like properties in lung cancer...

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Detalles Bibliográficos
Autores principales: Hung, Jung-Jyh, Kao, Ying-Shiun, Huang, Chi-Hung, Hsu, Wen-Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395617/
https://www.ncbi.nlm.nih.gov/pubmed/30816208
http://dx.doi.org/10.1038/s41598-019-39545-z